Efficacy and safety of endoscopic balloon dilation of symptomaticintestinal Crohn's disease strictures.

Mario Cottone, Mario Cottone, Mirko Olivo, Filippo Mocciaro, Rosalba Orlando, Daniela Scimeca, Luigi Maria Montalbano, Ambrogio Orlando, Gennaro D'Amico

Risultato della ricerca: Articlepeer review

70 Citazioni (Scopus)


AbstractAIM: To evaluate prospectively the clinical efficacy and safety of endoscopic hydrostatic balloon dilation in a consecutive cohort of symptomatic intestinal Crohn's disease strictures.METHODS: Between September 2003 and December 2008 we performed endoscopic balloon dilations in 37 Crohn's disease patients with 39 intestinal symptomatic strictures (4 naïve and 35 postoperative). Dilations were performed using a Rigiflex through-the-scope balloon. Clinical success rate was claimed if a patient remained asymptomatic and did not require surgery or further endoscopic dilation, following technical success. Actuarial curves of clinical, endoscopic (redilation) and surgical recurrence were obtained by Kaplan-Meier method. Demographic and disease variables were related to the main outcomes.RESULTS: After a mean follow-up of 26.3 months (range, 2-61 months), the long-term global benefit rate was 89% (33/37). The 1-2-3 years cumulative symptom-free rates were respectively: 76%, 55% and 46%. Four patients were operated upon. Technical success predicts a lower rate of surgery. There were no complications related to the endoscopic procedures.CONCLUSIONS: Endoscopic balloon dilation of symptomatic Crohn's disease strictures may achieve clinical benefit in many patients and is a valid alternative to surgery in the management of the disease. Dilation may be repeated in recurrent intestinal obstructions and appears safe without morbidity.
Lingua originaleEnglish
pagine (da-a)121-125
Numero di pagine5
RivistaDigestive and Liver Disease
Stato di pubblicazionePublished - 2011

All Science Journal Classification (ASJC) codes

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