Effects of high-frequency repetitive transcranial magnetic stimulation of primary motor cortex on laser-evoked potentials in migraine.

Filippo Brighina, Brigida Fierro, Claudia Serpino, Eleonora Vecchio, Vito Devito Francesco, Vittorio Sciruicchio, Marina De Tommaso, Paolo Lamberti, Paolo Livrea, Roberto Santostasi

Risultato della ricerca: Article

26 Citazioni (Scopus)

Abstract

The aim of this study was to examine the effects of high-frequency (HF) repetitive transcranial magnetic stimulation (rTMS) of the left primary motor cortex (M1) on subjective pain and evoked responses induced by laser stimulation (LEPs) of the contralateral hand and supraorbital zone in a cohort of migraine patients without aura during the inter-critical phase, and to compare the effects with those of non-migraine healthy controls. Thirteen migraine patients and 12 sex- and age-matched controls were evaluated. Each rTMS session consisted of 1,800 stimuli at a frequency of 5 Hz and 90% motor threshold intensity. Sham (control) rTMS was performed at the same stimulation position. The vertex LEP amplitude was reduced at the trigeminal and hand levels in the sham-placebo condition and after rTMS to a greater extent in the migraine patients than in healthy controls, while the laser pain rating was unaffected. These results suggest that HF rTMS of motor cortex and the sham procedure can both modulate pain-related evoked responses in migraine patients.
Lingua originaleEnglish
pagine (da-a)505-512
Numero di pagine8
RivistaTHE JOURNAL OF HEADACHE AND PAIN
Volume11
Stato di pubblicazionePublished - 2010

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Transcranial Magnetic Stimulation
Motor Cortex
Migraine Disorders
Pain
Lasers
Hand
Migraine without Aura
Placebos
Laser-Evoked Potentials

All Science Journal Classification (ASJC) codes

  • Clinical Neurology
  • Anesthesiology and Pain Medicine

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Effects of high-frequency repetitive transcranial magnetic stimulation of primary motor cortex on laser-evoked potentials in migraine. / Brighina, Filippo; Fierro, Brigida; Serpino, Claudia; Vecchio, Eleonora; Francesco, Vito Devito; Sciruicchio, Vittorio; De Tommaso, Marina; Lamberti, Paolo; Livrea, Paolo; Santostasi, Roberto.

In: THE JOURNAL OF HEADACHE AND PAIN, Vol. 11, 2010, pag. 505-512.

Risultato della ricerca: Article

Brighina, F, Fierro, B, Serpino, C, Vecchio, E, Francesco, VD, Sciruicchio, V, De Tommaso, M, Lamberti, P, Livrea, P & Santostasi, R 2010, 'Effects of high-frequency repetitive transcranial magnetic stimulation of primary motor cortex on laser-evoked potentials in migraine.', THE JOURNAL OF HEADACHE AND PAIN, vol. 11, pagg. 505-512.
Brighina, Filippo ; Fierro, Brigida ; Serpino, Claudia ; Vecchio, Eleonora ; Francesco, Vito Devito ; Sciruicchio, Vittorio ; De Tommaso, Marina ; Lamberti, Paolo ; Livrea, Paolo ; Santostasi, Roberto. / Effects of high-frequency repetitive transcranial magnetic stimulation of primary motor cortex on laser-evoked potentials in migraine. In: THE JOURNAL OF HEADACHE AND PAIN. 2010 ; Vol. 11. pagg. 505-512.
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abstract = "The aim of this study was to examine the effects of high-frequency (HF) repetitive transcranial magnetic stimulation (rTMS) of the left primary motor cortex (M1) on subjective pain and evoked responses induced by laser stimulation (LEPs) of the contralateral hand and supraorbital zone in a cohort of migraine patients without aura during the inter-critical phase, and to compare the effects with those of non-migraine healthy controls. Thirteen migraine patients and 12 sex- and age-matched controls were evaluated. Each rTMS session consisted of 1,800 stimuli at a frequency of 5 Hz and 90{\%} motor threshold intensity. Sham (control) rTMS was performed at the same stimulation position. The vertex LEP amplitude was reduced at the trigeminal and hand levels in the sham-placebo condition and after rTMS to a greater extent in the migraine patients than in healthy controls, while the laser pain rating was unaffected. These results suggest that HF rTMS of motor cortex and the sham procedure can both modulate pain-related evoked responses in migraine patients.",
author = "Filippo Brighina and Brigida Fierro and Claudia Serpino and Eleonora Vecchio and Francesco, {Vito Devito} and Vittorio Sciruicchio and {De Tommaso}, Marina and Paolo Lamberti and Paolo Livrea and Roberto Santostasi",
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T1 - Effects of high-frequency repetitive transcranial magnetic stimulation of primary motor cortex on laser-evoked potentials in migraine.

AU - Brighina, Filippo

AU - Fierro, Brigida

AU - Serpino, Claudia

AU - Vecchio, Eleonora

AU - Francesco, Vito Devito

AU - Sciruicchio, Vittorio

AU - De Tommaso, Marina

AU - Lamberti, Paolo

AU - Livrea, Paolo

AU - Santostasi, Roberto

PY - 2010

Y1 - 2010

N2 - The aim of this study was to examine the effects of high-frequency (HF) repetitive transcranial magnetic stimulation (rTMS) of the left primary motor cortex (M1) on subjective pain and evoked responses induced by laser stimulation (LEPs) of the contralateral hand and supraorbital zone in a cohort of migraine patients without aura during the inter-critical phase, and to compare the effects with those of non-migraine healthy controls. Thirteen migraine patients and 12 sex- and age-matched controls were evaluated. Each rTMS session consisted of 1,800 stimuli at a frequency of 5 Hz and 90% motor threshold intensity. Sham (control) rTMS was performed at the same stimulation position. The vertex LEP amplitude was reduced at the trigeminal and hand levels in the sham-placebo condition and after rTMS to a greater extent in the migraine patients than in healthy controls, while the laser pain rating was unaffected. These results suggest that HF rTMS of motor cortex and the sham procedure can both modulate pain-related evoked responses in migraine patients.

AB - The aim of this study was to examine the effects of high-frequency (HF) repetitive transcranial magnetic stimulation (rTMS) of the left primary motor cortex (M1) on subjective pain and evoked responses induced by laser stimulation (LEPs) of the contralateral hand and supraorbital zone in a cohort of migraine patients without aura during the inter-critical phase, and to compare the effects with those of non-migraine healthy controls. Thirteen migraine patients and 12 sex- and age-matched controls were evaluated. Each rTMS session consisted of 1,800 stimuli at a frequency of 5 Hz and 90% motor threshold intensity. Sham (control) rTMS was performed at the same stimulation position. The vertex LEP amplitude was reduced at the trigeminal and hand levels in the sham-placebo condition and after rTMS to a greater extent in the migraine patients than in healthy controls, while the laser pain rating was unaffected. These results suggest that HF rTMS of motor cortex and the sham procedure can both modulate pain-related evoked responses in migraine patients.

UR - http://hdl.handle.net/10447/55603

UR - https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3476225/

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JO - Journal of Headache and Pain

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SN - 1129-2369

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