Effects of berberine, curcumin, resveratrol alone and in combination with chemotherapeutic drugs and signal transduction inhibitors on cancer cellsâPower of nutraceuticals

Giuseppe Montalto, Melchiorre Cervello, Alberto M. Martelli, Saverio Candido, Stefano Ratti, Agnieszka Gizak, Kvin Lertpiriyapong, Dariusz Rakus, Pedro L. Rosalen, Massimo Libra, Linda S. Steelman, James A. Mccubrey, Paolo Lombardi, Ramiro M. Murata, Lucio Cocco, Giuseppe Montalto, Stephen L. Abrams

Risultato della ricerca: Articlepeer review

18 Citazioni (Scopus)

Abstract

Over the past fifty years, society has become aware of the importance of a healthy diet in terms of human fitness and longevity. More recently, the concept of the beneficial effects of certain components of our diet and other compounds, that are consumed often by different cultures in various parts of the world, has become apparent. These âhealthyâ components of our diet are often referred to as nutraceuticals and they can prevent/suppress: aging, bacterial, fungal and viral infections, diabetes, inflammation, metabolic disorders and cardiovascular diseases and have other health-enhancing effects. Moreover, they are now often being investigated because of their anti-cancer properties/potentials. Understanding the effects of various natural products on cancer cells may enhance their usage as anti-proliferative agents which may be beneficial for many health problems. In this manuscript, we discuss and demonstrate how certain nutraceuticals may enhance other anti-cancer drugs to suppress proliferation of cancer cells.
Lingua originaleEnglish
pagine (da-a)190-211
Numero di pagine22
RivistaAdvances in Biological Regulation
Volume67
Stato di pubblicazionePublished - 2018

All Science Journal Classification (ASJC) codes

  • Molecular Medicine
  • Molecular Biology
  • Genetics
  • Cancer Research

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