Effects of BDE-47 exposure on immune-related parameters of Mytilus galloprovincialis

Concetta Maria Messina, Andrea Santulli, María Ángeles Esteban, Concetta Gugliandolo, Andrea Santulli, Concetta Gugliandolo, Cristobal Espinosa Ruiz, Giuseppe Renda, Maria Morghese

Risultato della ricerca: Article

3 Citazioni (Scopus)

Abstract

The persistent pollutants polybrominated diphenyl ethers (PBDEs) have been demonstrated to produce several negative effects on marine organisms. Although Mytilus galloprovincialis was extensively studied as model system, the effects of PBDEs on the innate immune system of mussels remains unclear. In this study, except for the control treatment, specimens of M. galloprovincialis were fed with microalgae treated with increasing concentrations of PBDEs (maximum level 100 ng L−1 of BDE-47 per day). BDE-47 treatment was maintained for 15 days and then the animals were fed with the same control diet, without contaminants, for 15 days. Samples of haemolymph (HL) were obtained at T0, T15 and T30 days of the experiment to evaluate different parameters related to immunity, such as neutral red retention time, and peroxidase, protease, antiprotease, lysozyme and bactericidal activities. BDE-47 exposure for 15 days affected both the stability of haemocytes and humoral parameters. In addition, the obtained results indicated that, at 30 days, after 15 days of culture without contaminant, the immune parameters were still affected, as some of them did not return to the basal levels, and others remained stimulated. Overall the results indicate that BDE-47 exposures at environmentally realistic levels may affect various aspects of immune function in M. galloprovincialis, acting as stressor that can compromise the general welfare.
Lingua originaleEnglish
pagine (da-a)00-00
Numero di pagine34
RivistaAquatic Toxicology
Volume215
Stato di pubblicazionePublished - 2019

All Science Journal Classification (ASJC) codes

  • Aquatic Science
  • Health, Toxicology and Mutagenesis

Fingerprint Entra nei temi di ricerca di 'Effects of BDE-47 exposure on immune-related parameters of Mytilus galloprovincialis'. Insieme formano una fingerprint unica.

  • Cita questo

    Messina, C. M., Santulli, A., Esteban, M. Á., Gugliandolo, C., Santulli, A., Gugliandolo, C., Espinosa Ruiz, C., Renda, G., & Morghese, M. (2019). Effects of BDE-47 exposure on immune-related parameters of Mytilus galloprovincialis. Aquatic Toxicology, 215, 00-00.