Effectiveness of Rehabilitative Intervention on Pain, Postural Balance, and Quality of Life in Women with Multiple Vertebral Fragility Fractures: A Prospective Cohort Study

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Patients with vertebral fragility fractures often experience chronic pain, postural andbalance disorders, and poor quality of life (QoL). Although several studies have investigated the roleof rehabilitation in severe osteoporosis, the effectiveness of this intervention in patients with multiplevertebral fractures is poorly known. The aim of our longitudinal cohort study is to evaluate the effectiveness of rehabilitation, including postural training, resistance exercises, and visual stabilizationexercises, for a 7-week period, on the pain, postural balance, and QoL of subjects with at least twovertebral fragility fractures receiving denosumab and vitamin D. We investigated, before (T0) andafter (T1, at 7 weeks) rehabilitation, the following outcome measures on 28 patients: pain (NumericalRating Scale (NRS)), self-perceived QoL (36-Item Short Form Survey (SF-36) and Mini-OsteoporosisQuality of Life Questionnaire (Mini-OQOL)), dizziness (Dizziness Handicap Inventory (DHI-I)),mobility (Timed-Up and Go (TUG) test), and instrumental posturographic assessment (FreeMedposturography system). At the end of the treatment, improvements of pain and QoL were recorded.Pain relief was highly obtained in patients with more than two vertebral fractures. Moreover, asignificant functional improvement (TUG test) was found in those with two vertebral fractures,without any statistically significant change reported for other outcomes. Our findings suggest thatcombined intervention, including anti-osteoporotic drugs and postural rehabilitation, should beproposed to osteoporotic patients with multiple vertebral fract
Lingua originaleEnglish
Numero di pagine10
RivistaJournal of Functional Morphology and Kinesiology
Stato di pubblicazionePublished - 2021

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