Effect of the IMPase inhibitor L690,330 on sea urchin development

Risultato della ricerca: Article

5 Citazioni (Scopus)

Abstract

A variety of concentrations of the IMPase inhibitor L690,330 were added to sea urchin embryos. Immediate arrest of development was obtained for concentrations from 7.5 mM on. Concentrations lower than 3.5 mM permitted gastrulation but inhibited skeletogenesis and disturbed elongation along the animal-vegetal axis. The latter results are similar to those obtained by counteracting lithium effect with myoinositol, which are suggested to be due to partial relief of IMPase inhibition.
Lingua originaleEnglish
pagine (da-a)91-94
Numero di pagine4
RivistaCell Biology International
Volume22
Stato di pubblicazionePublished - 1998

All Science Journal Classification (ASJC) codes

  • Cell Biology

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Effect of the IMPase inhibitor L690,330 on sea urchin development. /.

In: Cell Biology International, Vol. 22, 1998, pag. 91-94.

Risultato della ricerca: Article

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title = "Effect of the IMPase inhibitor L690,330 on sea urchin development",
abstract = "A variety of concentrations of the IMPase inhibitor L690,330 were added to sea urchin embryos. Immediate arrest of development was obtained for concentrations from 7.5 mM on. Concentrations lower than 3.5 mM permitted gastrulation but inhibited skeletogenesis and disturbed elongation along the animal-vegetal axis. The latter results are similar to those obtained by counteracting lithium effect with myoinositol, which are suggested to be due to partial relief of IMPase inhibition.",
author = "Giovanni Giudice and Domenico Cascino and Fabiana Geraci and Gabriele Amore",
year = "1998",
language = "English",
volume = "22",
pages = "91--94",
journal = "Cell Biology International",
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T1 - Effect of the IMPase inhibitor L690,330 on sea urchin development

AU - Giudice, Giovanni

AU - Cascino, Domenico

AU - Geraci, Fabiana

AU - Amore, Gabriele

PY - 1998

Y1 - 1998

N2 - A variety of concentrations of the IMPase inhibitor L690,330 were added to sea urchin embryos. Immediate arrest of development was obtained for concentrations from 7.5 mM on. Concentrations lower than 3.5 mM permitted gastrulation but inhibited skeletogenesis and disturbed elongation along the animal-vegetal axis. The latter results are similar to those obtained by counteracting lithium effect with myoinositol, which are suggested to be due to partial relief of IMPase inhibition.

AB - A variety of concentrations of the IMPase inhibitor L690,330 were added to sea urchin embryos. Immediate arrest of development was obtained for concentrations from 7.5 mM on. Concentrations lower than 3.5 mM permitted gastrulation but inhibited skeletogenesis and disturbed elongation along the animal-vegetal axis. The latter results are similar to those obtained by counteracting lithium effect with myoinositol, which are suggested to be due to partial relief of IMPase inhibition.

UR - http://hdl.handle.net/10447/338453

UR - http://onlinelibrary.wiley.com/journal/10.1002/(ISSN)1095-8355

M3 - Article

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SP - 91

EP - 94

JO - Cell Biology International

JF - Cell Biology International

SN - 1065-6995

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