Effect of CYP1A1 gene polymorphisms on estrogen metabolism and bone density

Giovam Battista Rini; Nicola Napoli; Manuel Cagaanan; Reina C. Armamento-Villareal; Dennis T. Villareal; Steven Mumm; Linda Halstead; Sharmin Sheikh; Nicola Napoli

Effect of CYP1A1 gene polymorphisms on estrogen metabolism and bone density

Giovam Battista Rini, Nicola Napoli, Manuel Cagaanan, Reina C. Armamento-Villareal, Dennis T. Villareal, Steven Mumm, Linda Halstead, Sharmin Sheikh, Nicola Napoli

Risultato della ricerca: Article › peer review

58 Citazioni (Scopus)

Abstract

In this study, we evaluated the effect of polymorphisms of the CYP1A1 gene, linked to hormone-related cancers, on estrogen metabolism and BMD. We found that variants carrying the A allele (CA and AA) for the C4887A polymorphism have a significantly higher degree of estrogen catabolism and lower femoral BMD

Lingua originale	English
pagine (da-a)	232-239
Numero di pagine	8
Rivista	Journal of Bone and Mineral Research
Volume	20
Stato di pubblicazione	Published - 2005

All Science Journal Classification (ASJC) codes

Endocrinology, Diabetes and Metabolism
Orthopedics and Sports Medicine

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Effect of CYP1A1 gene polymorphisms on estrogen metabolism and bone density. / Rini, Giovam Battista; Napoli, Nicola; Cagaanan, Manuel; Armamento-Villareal, Reina C.; Villareal, Dennis T.; Mumm, Steven; Halstead, Linda; Sheikh, Sharmin; Napoli, Nicola.

In: Journal of Bone and Mineral Research, Vol. 20, 2005, pag. 232-239.

Risultato della ricerca: Article › peer review

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abstract = "In this study, we evaluated the effect of polymorphisms of the CYP1A1 gene, linked to hormone-related cancers, on estrogen metabolism and BMD. We found that variants carrying the A allele (CA and AA) for the C4887A polymorphism have a significantly higher degree of estrogen catabolism and lower femoral BMD",

author = "Rini, {Giovam Battista} and Nicola Napoli and Manuel Cagaanan and Armamento-Villareal, {Reina C.} and Villareal, {Dennis T.} and Steven Mumm and Linda Halstead and Sharmin Sheikh and Nicola Napoli",

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T1 - Effect of CYP1A1 gene polymorphisms on estrogen metabolism and bone density

AU - Rini, Giovam Battista

AU - Napoli, Nicola

AU - Cagaanan, Manuel

AU - Armamento-Villareal, Reina C.

AU - Villareal, Dennis T.

AU - Mumm, Steven

AU - Halstead, Linda

AU - Sheikh, Sharmin

AU - Napoli, Nicola

PY - 2005

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N2 - In this study, we evaluated the effect of polymorphisms of the CYP1A1 gene, linked to hormone-related cancers, on estrogen metabolism and BMD. We found that variants carrying the A allele (CA and AA) for the C4887A polymorphism have a significantly higher degree of estrogen catabolism and lower femoral BMD

AB - In this study, we evaluated the effect of polymorphisms of the CYP1A1 gene, linked to hormone-related cancers, on estrogen metabolism and BMD. We found that variants carrying the A allele (CA and AA) for the C4887A polymorphism have a significantly higher degree of estrogen catabolism and lower femoral BMD

UR - http://hdl.handle.net/10447/29011

M3 - Article

VL - 20

SP - 232

EP - 239

JO - Journal of Bone and Mineral Research

JF - Journal of Bone and Mineral Research

SN - 0884-0431

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