Effect of CYP1A1 gene polymorphisms on estrogen metabolism and bone density

Giovam Battista Rini, Nicola Napoli, Manuel Cagaanan, Reina C. Armamento-Villareal, Dennis T. Villareal, Steven Mumm, Linda Halstead, Sharmin Sheikh, Nicola Napoli

    Risultato della ricerca: Articlepeer review

    58 Citazioni (Scopus)

    Abstract

    In this study, we evaluated the effect of polymorphisms of the CYP1A1 gene, linked to hormone-related cancers, on estrogen metabolism and BMD. We found that variants carrying the A allele (CA and AA) for the C4887A polymorphism have a significantly higher degree of estrogen catabolism and lower femoral BMD
    Lingua originaleEnglish
    pagine (da-a)232-239
    Numero di pagine8
    RivistaJournal of Bone and Mineral Research
    Volume20
    Stato di pubblicazionePublished - 2005

    All Science Journal Classification (ASJC) codes

    • Endocrinology, Diabetes and Metabolism
    • Orthopedics and Sports Medicine

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