Early Treatment in HCV: Is it a Cost-Utility Option from the Italian Perspective?

Calogero Camma', Andrea Marcellusi, Raffaella Viti, Francesco Damele, Gloria Taliani, Francesco Saverio Mennini

Risultato della ricerca: Articlepeer review

12 Citazioni (Scopus)


In Italy, the Italian Pharmaceutical Agency (AIFA) criteria used F3-F4 fibrosis stages as the threshold to prioritise the treatment with interferon (IFN)-free regimens, while in genotype 1 chronic hepatitis C (G1 CHC) patients with fibrosis of liver stage 2, an approach with pegylated interferon (PEG-IFN)-based triple therapy with simeprevir was suggested. The key clinical question is whether, in an era of financial constraints, the application of a universal IFN-free strategy in naïve G1 CHC patients is feasible within a short time horizon. The aim of this study is to perform an economic analysis to estimate the cost-utility of the early innovative therapy in Italy for managing hepatitis C virus (HCV)-infected patients.
Lingua originaleEnglish
pagine (da-a)661-672
Numero di pagine12
RivistaClinical Drug Investigation
Stato di pubblicazionePublished - 2016

All Science Journal Classification (ASJC) codes

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