Early intestinal perforation secondary to congenital mesenteric defects

Mario Giuffre, Giovanni Corsello, Giovanni Corsello, Giuseppa Pinello, Mariaserena Lo Presti, Enrica Maria Agosta Cecala, Ingrid Anne Mandy Schierz, Cinzia Chiaramonte, Mario Giuffrè

Risultato della ricerca: Articlepeer review

1 Citazioni (Scopus)


Gastrointestinal perforation (GIP) in preterm neonates may be idiopathic, due to necrotizing enterocolitis (NEC), or mechanical obstruction. The predominant cause of GIP in the neonatal period is NEC. Differential diagnosis with congenital malformations, including mesenteric defects leading to internal hernias, is mandatory if the onset is early. We describe two newborns with trans-mesenteric herniation resulting in GIP, and we discuss the presence of possible additional risk factors such as prematurity and predisposing vascular disruption in connective tissue disorders (Ehlers-Danlos syndrome), twinning, and use of assisted reproductive technologies. These cases prompted us to review our exploratory laparotomies performed for intestinal obstruction, complicated/or not with perforation, to identify the frequency of neonatal trans-mesenteric hernias in a referral hospital. The prevalence of GIP and of internal hernia was 25% and 3.3%, respectively. In conclusion, time-onset and particular conditions associated with GIP should lead to a high index of suspicion for internal hernias in order to achieve appropriate diagnosis and therapy.
Lingua originaleEnglish
pagine (da-a)10-12
Numero di pagine3
RivistaJournal of Pediatric Surgery Case Reports
Stato di pubblicazionePublished - 2016

All Science Journal Classification (ASJC) codes

  • ???subjectarea.asjc.2700.2735???
  • ???subjectarea.asjc.2700.2746???


Entra nei temi di ricerca di 'Early intestinal perforation secondary to congenital mesenteric defects'. Insieme formano una fingerprint unica.

Cita questo