E26The effects of LIPUS on ctDNA release in the medium of NSCLC cell lines

Valentina Calo'; Marta Castiglia; Daniela Massihnia; Angela Listi'; Anna Barbara Di Stefano; Antonio Russo; Alessandro Perez; Cristiano Corso; Nadia Barraco; null Di Piazza; null Insalaco; Marta Castiglia; null Bronte; null Listì; Nadia Barraco; Daniela Massihnia; Alessandro Perez; null Guarini; Federica Grisafi; null Castellana; null Russo; Gaetano Barbato; Cristiano Corso; null Sorrentino; null Di Stefano; null Scoarughi; Valentina Calò; Domenica Matranga; Enrico Bronte; Florinda Di Piazza; Lavinia Insalaco; Luisa Castellana

E26The effects of LIPUS on ctDNA release in the medium of NSCLC cell lines

Valentina Calo', Marta Castiglia, Daniela Massihnia, Angela Listi', Anna Barbara Di Stefano, Antonio Russo, Alessandro Perez, Cristiano Corso, Nadia Barraco, Di Piazza, Insalaco, Marta Castiglia, Bronte, Listì, Nadia Barraco, Daniela Massihnia, Alessandro Perez, Guarini, Federica Grisafi, CastellanaRusso, Gaetano Barbato, Cristiano Corso, Sorrentino, Di Stefano, Scoarughi, Valentina Calò, Domenica Matranga, Enrico Bronte, Florinda Di Piazza, Lavinia Insalaco, Luisa Castellana

Risultato della ricerca: Other › peer review

Abstract

Low Intensity Pulsed Ultrasound (LIPUS) application has been shown to have anencouraging effect in inducing a transient pore formation through cellular membranes. Thispermeability condition has been demonstrated to be useful in enhancing gene and drug delivery.Nowadays, in the management of NSCLC patients, the use of liquid biopsy has entered the clinicalpractice. One of the main limits in the analysis of circulating tumor DNA is the low concentrationrate of nucleic acids in body fluids. Ultrasound stimulation (US) has been recently demonstrated tobe effective for the release of specific circulating tumor biomarkers in many mouse models. Wedemonstrated the role of US in inducing the release of tumor DNA fragments (rtDNA) in NSCLCwithout inducing any apoptotic or necrotic event.

Lingua originale	English
Numero di pagine	0
Stato di pubblicazione	Published - 2017

All Science Journal Classification (ASJC) codes

???subjectarea.asjc.2700.2720???
???subjectarea.asjc.2700.2730???

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Calo', V , Castiglia, M , Massihnia, D , Listi', A , Di Stefano, AB , Russo, A , Perez, A , Corso, C , Barraco, N, Di Piazza, Insalaco, Castiglia, M, Bronte, Listì, Barraco, N, Massihnia, D, Perez, A, Guarini, Grisafi, F, Castellana, Russo, Barbato, G, Corso, C, Sorrentino, Di Stefano, Scoarughi, Calò, V, Matranga, D, Bronte, E, Di Piazza, F, Insalaco, L & Castellana, L 2017, 'E26The effects of LIPUS on ctDNA release in the medium of NSCLC cell lines'.

@conference{35ef1729e9a143a9a0621693c336a81e,

title = "E26The effects of LIPUS on ctDNA release in the medium of NSCLC cell lines",

abstract = "Low Intensity Pulsed Ultrasound (LIPUS) application has been shown to have anencouraging effect in inducing a transient pore formation through cellular membranes. Thispermeability condition has been demonstrated to be useful in enhancing gene and drug delivery.Nowadays, in the management of NSCLC patients, the use of liquid biopsy has entered the clinicalpractice. One of the main limits in the analysis of circulating tumor DNA is the low concentrationrate of nucleic acids in body fluids. Ultrasound stimulation (US) has been recently demonstrated tobe effective for the release of specific circulating tumor biomarkers in many mouse models. Wedemonstrated the role of US in inducing the release of tumor DNA fragments (rtDNA) in NSCLCwithout inducing any apoptotic or necrotic event.",

author = "Valentina Calo' and Marta Castiglia and Daniela Massihnia and Angela Listi' and {Di Stefano}, {Anna Barbara} and Antonio Russo and Alessandro Perez and Cristiano Corso and Nadia Barraco and {Di Piazza} and Insalaco and Marta Castiglia and Bronte and List{\`i} and Nadia Barraco and Daniela Massihnia and Alessandro Perez and Guarini and Federica Grisafi and Castellana and Russo and Gaetano Barbato and Cristiano Corso and Sorrentino and {Di Stefano} and Scoarughi and Valentina Cal{\`o} and Domenica Matranga and Enrico Bronte and {Di Piazza}, Florinda and Lavinia Insalaco and Luisa Castellana",

year = "2017",

language = "English",

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TY - CONF

T1 - E26The effects of LIPUS on ctDNA release in the medium of NSCLC cell lines

AU - Calo', Valentina

AU - Castiglia, Marta

AU - Massihnia, Daniela

AU - Listi', Angela

AU - Di Stefano, Anna Barbara

AU - Russo, Antonio

AU - Perez, Alessandro

AU - Corso, Cristiano

AU - Barraco, Nadia

AU - Di Piazza, null

AU - Insalaco, null

AU - Castiglia, Marta

AU - Bronte, null

AU - Listì, null

AU - Barraco, Nadia

AU - Massihnia, Daniela

AU - Perez, Alessandro

AU - Guarini, null

AU - Grisafi, Federica

AU - Castellana, null

AU - Russo, null

AU - Barbato, Gaetano

AU - Corso, Cristiano

AU - Sorrentino, null

AU - Di Stefano, null

AU - Scoarughi, null

AU - Calò, Valentina

AU - Matranga, Domenica

AU - Bronte, Enrico

AU - Di Piazza, Florinda

AU - Insalaco, Lavinia

AU - Castellana, Luisa

PY - 2017

Y1 - 2017

N2 - Low Intensity Pulsed Ultrasound (LIPUS) application has been shown to have anencouraging effect in inducing a transient pore formation through cellular membranes. Thispermeability condition has been demonstrated to be useful in enhancing gene and drug delivery.Nowadays, in the management of NSCLC patients, the use of liquid biopsy has entered the clinicalpractice. One of the main limits in the analysis of circulating tumor DNA is the low concentrationrate of nucleic acids in body fluids. Ultrasound stimulation (US) has been recently demonstrated tobe effective for the release of specific circulating tumor biomarkers in many mouse models. Wedemonstrated the role of US in inducing the release of tumor DNA fragments (rtDNA) in NSCLCwithout inducing any apoptotic or necrotic event.

AB - Low Intensity Pulsed Ultrasound (LIPUS) application has been shown to have anencouraging effect in inducing a transient pore formation through cellular membranes. Thispermeability condition has been demonstrated to be useful in enhancing gene and drug delivery.Nowadays, in the management of NSCLC patients, the use of liquid biopsy has entered the clinicalpractice. One of the main limits in the analysis of circulating tumor DNA is the low concentrationrate of nucleic acids in body fluids. Ultrasound stimulation (US) has been recently demonstrated tobe effective for the release of specific circulating tumor biomarkers in many mouse models. Wedemonstrated the role of US in inducing the release of tumor DNA fragments (rtDNA) in NSCLCwithout inducing any apoptotic or necrotic event.

UR - http://hdl.handle.net/10447/245240

M3 - Other

ER -

E26The effects of LIPUS on ctDNA release in the medium of NSCLC cell lines

Abstract

All Science Journal Classification (ASJC) codes

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