Double copies of blaKPC-3::Tn4401a on an IncX3 plasmid in Klebsiella pneumoniae successful clone ST512 from Italy

Celestino Bonura, Caterina Mammina, Claudia Feudi, João Pires, Laura Villa, Andrea Endimiani, Alessandra Carattoli, Daniela Fortini

Risultato della ricerca: Article

14 Citazioni (Scopus)

Abstract

A carbapenem-resistant sequence type 512 (ST512) Klebsiella pneumoniae carbapenemase 3 (KPC-3)-producing K. pneumoniae strain showing a novel variant plasmid content was isolated in Palermo, Italy, in 2014. ST512 is a worldwide successful clone associated with the spread of blaKPC genes located on the IncFIIk pKpQIL plasmid. In our ST512 strain, the blaKPC-3 gene was unusually located on an IncX3 plasmid, whose complete sequence was determined. Two copies of blaKPC-3::Tn4401a caused by intramolecular transposition events were detected in the plasmid.
Lingua originaleEnglish
pagine (da-a)646-649
Numero di pagine4
RivistaAntimicrobial Agents and Chemotherapy
Volume60
Stato di pubblicazionePublished - 2016

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All Science Journal Classification (ASJC) codes

  • Pharmacology
  • Pharmacology (medical)
  • Infectious Diseases

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