Does the level of serum antimüllerian hormone predict ovulatory function in women with polycystic ovary syndrome with aging?

Pasquale Mansueto, Enrico Carmina, Roger Lobo, Daniel Kort, Anna Maria Campagna

Risultato della ricerca: Article

16 Citazioni (Scopus)

Abstract

AbstractOBJECTIVE:To determine possible prediction of regular menses with aging in anovulatory women with polycystic ovary syndrome (PCOS).DESIGN:Cohort.SETTING:Academic practice.PATIENT(S):A total of 54 anovulatory women with PCOS and 28 age- and weight-matched control subjects.INTERVENTION(S):Blood and ovarian ultrasound at baseline and after 5 years. MAJOR OUTCOME MEASURE(S): Serum antimüllerian hormone (AMH), gonadotropins, androgens, insulin sensitivity, and ovarian ultrasound.RESULT(S):After 5 years, there was a significant decrease in AMH in women with PCOS and control subjects (10 of 54 anovulatory women became ovulatory after 5 years). There was a significant negative correlation between baseline serum AMH and ovulatory function after 5 years. However, baseline serum AMH ≤ 4 ng/mL was associated with ovulatory function.CONCLUSION(S):Serum AMH may help predict ovulatory function with aging in anovulatory women with PCOS.Copyright © 2012 American Society for Reproductive Medicine. Published by Elsevier Inc. All rights reserved.
Lingua originaleEnglish
pagine (da-a)1043-1046
Numero di pagine4
RivistaFertility and Sterility
Volume98
Stato di pubblicazionePublished - 2012

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All Science Journal Classification (ASJC) codes

  • Reproductive Medicine
  • Obstetrics and Gynaecology

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