AbstractOBJECTIVE:To determine possible prediction of regular menses with aging in anovulatory women with polycystic ovary syndrome (PCOS).DESIGN:Cohort.SETTING:Academic practice.PATIENT(S):A total of 54 anovulatory women with PCOS and 28 age- and weight-matched control subjects.INTERVENTION(S):Blood and ovarian ultrasound at baseline and after 5 years. MAJOR OUTCOME MEASURE(S): Serum antimüllerian hormone (AMH), gonadotropins, androgens, insulin sensitivity, and ovarian ultrasound.RESULT(S):After 5 years, there was a significant decrease in AMH in women with PCOS and control subjects (10 of 54 anovulatory women became ovulatory after 5 years). There was a significant negative correlation between baseline serum AMH and ovulatory function after 5 years. However, baseline serum AMH ≤ 4 ng/mL was associated with ovulatory function.CONCLUSION(S):Serum AMH may help predict ovulatory function with aging in anovulatory women with PCOS.Copyright © 2012 American Society for Reproductive Medicine. Published by Elsevier Inc. All rights reserved.
|Numero di pagine||4|
|Rivista||Fertility and Sterility|
|Stato di pubblicazione||Published - 2012|
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