Differential diagnostic features of bone marrow biopsies in essential thrombocythemia

Risultato della ricerca: Conference contribution

Abstract

Essential Thrombocythemia (ET) is a chronic myeloproliferative disorder (CMPD) characterizedby a high platelet count and originating from a multipotent stem cell. For a long time, according to Polycythaemia Vera Study Group (PVSG) criteria, ET diagnosis has not included histopathological data. Bone Marrow (BM) histology was used only to exclude previous or other subtypes of Ph-CMD or Myelodysplastic syndromes (MDS). In addition, the lack of any cytogenetic or molecular-biological marker has made the discrimination between ET and cases of Reactive Thrombocytosys (RT) without a well known cause quite problematic. Analogously, the distinction of ET from the other Ph- CMPDs with similar clinical presentation can be challenging
Lingua originaleEnglish
Titolo della pubblicazione ospiteProceeding of European MPD Workshop on Clinical and Pathological Features of Ph1- MPDs
Pagine72-74
Numero di pagine3
Stato di pubblicazionePublished - 2004

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