Dietary supplements as surrogate of Mediterranean Diet in healthy smoking subjects

Calogero Caruso, Giuseppina Candore, Francesca Di Gaudio, Claudia Maria Rizzo, Annalisa Barera, Sonya Vasto, Serena Indelicato, Roberto Monastero, Giulia Accardi, Anna Aiello, Emilio Italiano, Francesca Di Gaudio, Calogero Caruso, Sonya Vasto, Serena Indelicato, Damiano Galimberti

Risultato della ricerca: Articlepeer review

3 Citazioni (Scopus)


The interventions to slow ageing, favouring active life expectancy, represent the new perspectives in ageing investigation. Some mechanisms that delay or prevent the onset of ageing pathologies have been identified. Between them, a healthy lifestyle seems to reduce many risk factors. In particular, eating habits represent the most concrete, low cost way to act on ageing process. Mediterranean diet has received much attention since it has been consistently demonstrated its anti-oxidant and anti-inflammatory effects. Unfortunately, many people follow a Western diet, poor in phytochemicals that represent the main source of beneficial effects of this dietary pattern. So, supplements administration should be considered, especially in subjects exposed to high level of oxidative stress and inflammation. So, we tested the properties of a commercial food supplement containing a series of plant polyphenols in combination with caffeine, bioperine (black pepper extract) and selenium in smoking healthy volunteers. Fifty participants have been recruited and hematochemical analyses and biochemistry tests have been performed, before and after 60 days of supplement intake. Thirteen subjects dropped out of the study. At the end of the intervention, the variation of inflammatory and oxidant markers has been evaluated, measuring urinary isoprostanes, serum advanced glycation end products, and oxidized low-density lipoproteins. The results showed that this supplement exhibits promising anti-oxidant and anti-inflammatory responses, especially in women, highlighting the role of supplementation in certain groups of subjects, for the control of oxidative stress as well as inflammatory status. So, its intake should be useful in delaying the onset of age-related diseases.
Lingua originaleEnglish
pagine (da-a)37-43
Numero di pagine7
RivistaRejuvenation Research
Stato di pubblicazionePublished - 2017

All Science Journal Classification (ASJC) codes

  • ???subjectarea.asjc.1300.1302???
  • ???subjectarea.asjc.2700.2717???


Entra nei temi di ricerca di 'Dietary supplements as surrogate of Mediterranean Diet in healthy smoking subjects'. Insieme formano una fingerprint unica.

Cita questo