Determinants of short term recurrence rate of endometriosis

Antonino Perino, Fabio Parazzini, Gianluca Bracco, Maurizio Rosati, Mario Massobrio, Mario Vicino, Maurizio Rosati, Fabio Di Stefano, Lorenzo Aguzzoli, Simona Moroni, Fabio Di Stefano, Andrea Pasini, Fabio Di Stefano, Mario Massobrio, Fabio Di Stefano, Carlo Bertulessi, Gian Franco Trossarelli, Paolo Beretta, Mario Massobrio, Sergio Shonauer

Risultato della ricerca: Articlepeer review

45 Citazioni (Scopus)


Objective: To analyse the frequency and the determinants of recurrence rate of clinically detectable endometriosis.Study design: Prospective cohort multicenter study. Eligible for the study were all women observed for the first time during the periodJanuary–June 1998 at the participating centres with a laparoscopically confirmed first diagnosis of endometriosis. After diagnosis, patientswere treated according to standard care of each centre and desire for pregnancy. The protocol required all women to be followed up at thecentre each year for 2 years with a clinical examination, an ultrasound pelvic examination and a CA125 assay, unless pregnancy occurred.Second look laparoscopy was performed on a clinical basis.Results: A total of 311 women (median age 36 years) entered the study. The two-year recurrence rate was 5.7% among cases stage I-II and14.4% among stage III–IV (x21 adjusted for indication for surgery, p < 0.05). The recurrence rates tended to increase with age, being 4.6%among women aged 20–30 and 13.1% among women aged >30, but this finding was not statistically significant.Conclusion: The recurrence rate of clinically detectable endometriosis tends to be higher in older women with advanced stages of the diseaseand lower in women with infertility
Lingua originaleEnglish
pagine (da-a)216-219
Numero di pagine4
Stato di pubblicazionePublished - 2005

All Science Journal Classification (ASJC) codes

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