Detectable interleukin-9 plasma levels are associated with impaired cardiopulmonary functional capacity and all-cause mortality in patients with chronic heart failure

Gabriella Misiano; Michele Arcopinto; Carlo Vigorito; Emanuele Bobbio; Andrea Salzano; Andrea M. Isidori; Eduardo Bossone; Alberto M. Marra; Pasquale Perrone-Filardi; Antonio Cittadini; Francesco Ferrara; Francesco Giallauria; Olga Vriz; Vincenzo Triggiani; Raffaele Napoli; Francesco Saccà; Salvatore Milano

Detectable interleukin-9 plasma levels are associated with impaired cardiopulmonary functional capacity and all-cause mortality in patients with chronic heart failure

Gabriella Misiano, Michele Arcopinto, Carlo Vigorito, Emanuele Bobbio, Andrea Salzano, Andrea M. Isidori, Eduardo Bossone, Alberto M. Marra, Pasquale Perrone-Filardi, Antonio Cittadini, Francesco Ferrara, Francesco Giallauria, Olga Vriz, Vincenzo Triggiani, Raffaele Napoli, Francesco Saccà, Salvatore Milano

Biomedicina, Neuroscienze e Diagnostica avanzata

Risultato della ricerca: Article › peer review

18 Citazioni (Scopus)

Abstract

Inflammatory activation plays a pivotal role in chronic heart failure (CHF) through the increased expression of pro-inflammatory cytokines [1]. Decreased plasma levels of Interleukin (IL-) 5, IL-7 and Interferon-γ (IFN-γ) and increased levels of IL-9 have been already described in CHF [2], and a negative correlation was also reported between IL-9 and left ventricular ejection fraction (LVEF) [2]. Yet, there are only limited data exploring the association between cytokines and functional capacity in CHF and their prognostic role [3]; therefore, primary end-point of the current study was to evaluate all-cause mortality according to changes in cytokines plasma levels in CHF patients.

Lingua originale	English
pagine (da-a)	114-117
Numero di pagine	4
Rivista	INTERNATIONAL JOURNAL OF CARDIOLOGY
Volume	209
Stato di pubblicazione	Published - 2016

All Science Journal Classification (ASJC) codes

Cardiology and Cardiovascular Medicine

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Misiano, G., Arcopinto, M., Vigorito, C., Bobbio, E., Salzano, A., Isidori, A. M., Bossone, E., Marra, A. M., Perrone-Filardi, P., Cittadini, A., Ferrara, F., Giallauria, F., Vriz, O., Triggiani, V., Napoli, R., Saccà, F., & Milano, S. (2016). Detectable interleukin-9 plasma levels are associated with impaired cardiopulmonary functional capacity and all-cause mortality in patients with chronic heart failure. INTERNATIONAL JOURNAL OF CARDIOLOGY, 209, 114-117.

Detectable interleukin-9 plasma levels are associated with impaired cardiopulmonary functional capacity and all-cause mortality in patients with chronic heart failure. / Misiano, Gabriella; Arcopinto, Michele; Vigorito, Carlo; Bobbio, Emanuele; Salzano, Andrea; Isidori, Andrea M.; Bossone, Eduardo; Marra, Alberto M.; Perrone-Filardi, Pasquale; Cittadini, Antonio; Ferrara, Francesco; Giallauria, Francesco; Vriz, Olga; Triggiani, Vincenzo; Napoli, Raffaele; Saccà, Francesco; Milano, Salvatore.

In: INTERNATIONAL JOURNAL OF CARDIOLOGY, Vol. 209, 2016, pag. 114-117.

Risultato della ricerca: Article › peer review

Misiano, G, Arcopinto, M, Vigorito, C, Bobbio, E, Salzano, A, Isidori, AM, Bossone, E, Marra, AM, Perrone-Filardi, P, Cittadini, A, Ferrara, F, Giallauria, F, Vriz, O, Triggiani, V, Napoli, R, Saccà, F & Milano, S 2016, 'Detectable interleukin-9 plasma levels are associated with impaired cardiopulmonary functional capacity and all-cause mortality in patients with chronic heart failure', INTERNATIONAL JOURNAL OF CARDIOLOGY, vol. 209, pagg. 114-117.

Misiano, Gabriella ; Arcopinto, Michele ; Vigorito, Carlo ; Bobbio, Emanuele ; Salzano, Andrea ; Isidori, Andrea M. ; Bossone, Eduardo ; Marra, Alberto M. ; Perrone-Filardi, Pasquale ; Cittadini, Antonio ; Ferrara, Francesco ; Giallauria, Francesco ; Vriz, Olga ; Triggiani, Vincenzo ; Napoli, Raffaele ; Saccà, Francesco ; Milano, Salvatore. / Detectable interleukin-9 plasma levels are associated with impaired cardiopulmonary functional capacity and all-cause mortality in patients with chronic heart failure. In: INTERNATIONAL JOURNAL OF CARDIOLOGY. 2016 ; Vol. 209. pagg. 114-117.

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title = "Detectable interleukin-9 plasma levels are associated with impaired cardiopulmonary functional capacity and all-cause mortality in patients with chronic heart failure",

abstract = "Inflammatory activation plays a pivotal role in chronic heart failure (CHF) through the increased expression of pro-inflammatory cytokines [1]. Decreased plasma levels of Interleukin (IL-) 5, IL-7 and Interferon-γ (IFN-γ) and increased levels of IL-9 have been already described in CHF [2], and a negative correlation was also reported between IL-9 and left ventricular ejection fraction (LVEF) [2]. Yet, there are only limited data exploring the association between cytokines and functional capacity in CHF and their prognostic role [3]; therefore, primary end-point of the current study was to evaluate all-cause mortality according to changes in cytokines plasma levels in CHF patients. ",

author = "Gabriella Misiano and Michele Arcopinto and Carlo Vigorito and Emanuele Bobbio and Andrea Salzano and Isidori, {Andrea M.} and Eduardo Bossone and Marra, {Alberto M.} and Pasquale Perrone-Filardi and Antonio Cittadini and Francesco Ferrara and Francesco Giallauria and Olga Vriz and Vincenzo Triggiani and Raffaele Napoli and Francesco Sacc{\`a} and Salvatore Milano",

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T1 - Detectable interleukin-9 plasma levels are associated with impaired cardiopulmonary functional capacity and all-cause mortality in patients with chronic heart failure

AU - Misiano, Gabriella

AU - Arcopinto, Michele

AU - Vigorito, Carlo

AU - Bobbio, Emanuele

AU - Salzano, Andrea

AU - Isidori, Andrea M.

AU - Bossone, Eduardo

AU - Marra, Alberto M.

AU - Perrone-Filardi, Pasquale

AU - Cittadini, Antonio

AU - Ferrara, Francesco

AU - Giallauria, Francesco

AU - Vriz, Olga

AU - Triggiani, Vincenzo

AU - Napoli, Raffaele

AU - Saccà, Francesco

AU - Milano, Salvatore

PY - 2016

Y1 - 2016

N2 - Inflammatory activation plays a pivotal role in chronic heart failure (CHF) through the increased expression of pro-inflammatory cytokines [1]. Decreased plasma levels of Interleukin (IL-) 5, IL-7 and Interferon-γ (IFN-γ) and increased levels of IL-9 have been already described in CHF [2], and a negative correlation was also reported between IL-9 and left ventricular ejection fraction (LVEF) [2]. Yet, there are only limited data exploring the association between cytokines and functional capacity in CHF and their prognostic role [3]; therefore, primary end-point of the current study was to evaluate all-cause mortality according to changes in cytokines plasma levels in CHF patients.

AB - Inflammatory activation plays a pivotal role in chronic heart failure (CHF) through the increased expression of pro-inflammatory cytokines [1]. Decreased plasma levels of Interleukin (IL-) 5, IL-7 and Interferon-γ (IFN-γ) and increased levels of IL-9 have been already described in CHF [2], and a negative correlation was also reported between IL-9 and left ventricular ejection fraction (LVEF) [2]. Yet, there are only limited data exploring the association between cytokines and functional capacity in CHF and their prognostic role [3]; therefore, primary end-point of the current study was to evaluate all-cause mortality according to changes in cytokines plasma levels in CHF patients.

UR - http://hdl.handle.net/10447/250599

M3 - Article

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