Cytotoxic activity of some natural and synthetic guaianolides

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46 Citazioni (Scopus)

Abstract

Several natural guaianolides and synthetic derivatives of repin (1) were tested and found to be active against tumor cell replication. Repin (1) and both mono- and di-halohydrin analogues (2, 7-9, 11, 12) showed significant antitumor potency. A more effective compound (17) was obtained by esterificating repin with the paclitaxel side chain
Lingua originaleEnglish
pagine (da-a)1042-1046
Numero di pagine5
RivistaJournal of Natural Products
Volume68
Stato di pubblicazionePublished - 2005

All Science Journal Classification (ASJC) codes

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  • ???subjectarea.asjc.1600.1601???
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  • ???subjectarea.asjc.1300.1313???
  • ???subjectarea.asjc.3000.3004???
  • ???subjectarea.asjc.3000.3003???
  • ???subjectarea.asjc.2700.2707???
  • ???subjectarea.asjc.1600.1605???
  • ???subjectarea.asjc.3000.3002???

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