Cytotoxic activity of diterpenoids isolated from the aerial parts of Elaeoselinum asclepium subsp. meoides

Sergio Rosselli, Maurizio Bruno, Antonella Maria Maggio, Carlo Irace, Nicola Mascolo, Carmen Formisano, Carmen Maffettone

Risultato della ricerca: Article

10 Citazioni (Scopus)

Abstract

The phytochemical investigation of the acetone extract of the aerial parts of Elaeoselinum asclepium (L.) Bertol. subsp. meoides (Desf.) Fiori afforded several known diterpenoids as well as meoidic acid (5), new in the literature. The cytotoxic activities of elasclepic acid (1), ent-atis-16-en-19-oic acid (2), ent-beyer-15-en-19-oic acid (3), ent-kaur-16-en-19-oic acid (4) and meoidic acid (5) were investigated on rat glioma C6 cells by evaluation of cell growth inhibition.
Lingua originaleEnglish
pagine (da-a)1285-1287
Numero di pagine3
RivistaPlanta Medica
Volume74
Stato di pubblicazionePublished - 2008

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All Science Journal Classification (ASJC) codes

  • Analytical Chemistry
  • Molecular Medicine
  • Pharmacology
  • Pharmaceutical Science
  • Drug Discovery
  • Complementary and alternative medicine
  • Organic Chemistry

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