1. World J Gastroenterol. 2006 Aug 14;12(30):4813-8.Cytomegalovirus and inflammatory bowel disease: is there a link?Criscuoli V, Rizzuto MR, Cottone M.Division of Internal Medicine, University of Palermo, V. Cervello Hospital ViaTrabucco 180, Palermo 90100, Italy.The objective of this report is to give an overall view of the epidemiological,clinical, diagnostic and therapeutic features of Cytomegalovirus (CMV) infection in inflammatory bowel disease (IBD). A review of published reports on this topic was carried out, with particular attention paid to the selection of patientsincluded in studies and the diagnostic methods employed. CMV is frequentlyassociated with IBD. In some cases, CMV infection is associated with a pooroutcome but it is not clear which patients are more likely to be affected and in which stage of the disease. The use of anti-viral therapy in IBD is controversialand an empirical study with controls is needed. The natural history of CMVinfection related to the development and treatment of IBD has not been clarified but it is important to take it in consideration because of the possibility ofviral persistence in the immunocompromised host and viral interaction with theimmune system.
|Numero di pagine||6|
|Rivista||World Journal of Gastroenterology|
|Stato di pubblicazione||Published - 2006|
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