Abstract
Lingua originale | English |
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Numero di pagine | 0 |
Rivista | Default journal |
Volume | 2018 |
Stato di pubblicazione | Published - 2018 |
All Science Journal Classification (ASJC) codes
- Biochemistry, Genetics and Molecular Biology(all)
- Immunology and Microbiology(all)
Cita questo
Could the Combined Administration of Bone Antiresorptive Drug, Taxanes, and Corticosteroids Worsen Medication Related Osteonecrosis of the Jaws in Cancer Patients? / Campisi, Giuseppina; Di Fede, Olga; Oteri, Giacomo; Marcianò, Antonia; Picone, Antonio; Nucera, Riccardo; Morreale, Ilaria; Panzarella, Vera.
In: Default journal, Vol. 2018, 2018.Risultato della ricerca: Article
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TY - JOUR
T1 - Could the Combined Administration of Bone Antiresorptive Drug, Taxanes, and Corticosteroids Worsen Medication Related Osteonecrosis of the Jaws in Cancer Patients?
AU - Campisi, Giuseppina
AU - Di Fede, Olga
AU - Oteri, Giacomo
AU - Marcianò, Antonia
AU - Picone, Antonio
AU - Nucera, Riccardo
AU - Morreale, Ilaria
AU - Panzarella, Vera
PY - 2018
Y1 - 2018
N2 - The study presents a report of 58 metastatic cancer patients who developed osteonecrosis of the jaws after being treated with zoledronic acid and taxanes, plus corticosteroids. A retrospective analysis of data registered in the archives of two Italian osteonecrosis of the jaws treatment centers, who are based at the University of Messina and at the University of Palermo, was performed in order to study, in these patients, demographic data and characteristics such as frequency of cancer location, lines of therapy, frequency of cancer drugs, presence/absence of oral trigger, number, location, and stage of jaw osteonecrosis. It was found that the majority of patients developed advanced stages of osteonecrosis, frequently complicated with infection. It was hypothesized that the concurrent administration of chemotherapeutic agents could be eventually considered as a factor able to allow a faster worsening of the clinical manifestation through the exacerbation of soft tissue defects, due to chemotherapy drugs.
AB - The study presents a report of 58 metastatic cancer patients who developed osteonecrosis of the jaws after being treated with zoledronic acid and taxanes, plus corticosteroids. A retrospective analysis of data registered in the archives of two Italian osteonecrosis of the jaws treatment centers, who are based at the University of Messina and at the University of Palermo, was performed in order to study, in these patients, demographic data and characteristics such as frequency of cancer location, lines of therapy, frequency of cancer drugs, presence/absence of oral trigger, number, location, and stage of jaw osteonecrosis. It was found that the majority of patients developed advanced stages of osteonecrosis, frequently complicated with infection. It was hypothesized that the concurrent administration of chemotherapeutic agents could be eventually considered as a factor able to allow a faster worsening of the clinical manifestation through the exacerbation of soft tissue defects, due to chemotherapy drugs.
UR - http://hdl.handle.net/10447/297290
UR - http://www.hindawi.com/journals/biomed/
M3 - Article
VL - 2018
JO - Default journal
JF - Default journal
ER -