Correlation between FIX genotype and pharmacokinetics of Nonacog alpha according to a multicentre Italian study

Mariasanta Napolitano, Massimo Morfini, Barillari, Paolo Radossi, Dragani, Paladino, Maria Gabriella Mazzucconi, Giuseppe Tagariello, Rossetti, Giovanni Di Minno

Risultato della ricerca: Article

9 Citazioni (Scopus)

Abstract

Pharmacokinetic (PK) studies on recombinant FIX concentrate, Nonacog alpha, were conducted with different sampling time designs which gave rise to not complete and homogenous outcomes. In addition, patient's FIX genotype/PK relationship has never been investigated.
Lingua originaleEnglish
pagine (da-a)n/a-n/a
Numero di pagine6
RivistaHaemophilia
Stato di pubblicazionePublished - 2016

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Multicenter Studies
Pharmacokinetics
Genotype

All Science Journal Classification (ASJC) codes

  • Hematology
  • Genetics(clinical)

Cita questo

Napolitano, M., Morfini, M., Barillari, Radossi, P., Dragani, Paladino, ... Di Minno, G. (2016). Correlation between FIX genotype and pharmacokinetics of Nonacog alpha according to a multicentre Italian study. Haemophilia, n/a-n/a.

Correlation between FIX genotype and pharmacokinetics of Nonacog alpha according to a multicentre Italian study. / Napolitano, Mariasanta; Morfini, Massimo; Barillari; Radossi, Paolo; Dragani; Paladino; Mazzucconi, Maria Gabriella; Tagariello, Giuseppe; Rossetti; Di Minno, Giovanni.

In: Haemophilia, 2016, pag. n/a-n/a.

Risultato della ricerca: Article

Napolitano, M, Morfini, M, Barillari, Radossi, P, Dragani, Paladino, Mazzucconi, MG, Tagariello, G, Rossetti & Di Minno, G 2016, 'Correlation between FIX genotype and pharmacokinetics of Nonacog alpha according to a multicentre Italian study', Haemophilia, pagg. n/a-n/a.
Napolitano, Mariasanta ; Morfini, Massimo ; Barillari ; Radossi, Paolo ; Dragani ; Paladino ; Mazzucconi, Maria Gabriella ; Tagariello, Giuseppe ; Rossetti ; Di Minno, Giovanni. / Correlation between FIX genotype and pharmacokinetics of Nonacog alpha according to a multicentre Italian study. In: Haemophilia. 2016 ; pagg. n/a-n/a.
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AU - Napolitano, Mariasanta

AU - Morfini, Massimo

AU - Barillari, null

AU - Radossi, Paolo

AU - Dragani, null

AU - Paladino, null

AU - Mazzucconi, Maria Gabriella

AU - Tagariello, Giuseppe

AU - Rossetti, null

AU - Di Minno, Giovanni

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AB - Pharmacokinetic (PK) studies on recombinant FIX concentrate, Nonacog alpha, were conducted with different sampling time designs which gave rise to not complete and homogenous outcomes. In addition, patient's FIX genotype/PK relationship has never been investigated.

KW - DNA Recombinant proteins

KW - factor IX

KW - genotype

KW - haemophilia B

KW - pharmacokinetics

UR - http://hdl.handle.net/10447/174312

M3 - Article

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JF - Haemophilia

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