Congenital pulmonary airway malformation in adult: report of two rare cases and literature review

Domenico Albano, Massimo Midiri, Tommaso Vincenzo Bartolotta, Massimo Galia, Cesare Gagliardo, Alberto Bruno, Antonio Sidoti Pinto, Claudio Leto, Dario Giambelluca, Giuseppe Cutaia, Giuseppe Salvaggio, Leonardo Salvaggio

Risultato della ricerca: Article

Abstract

Congenital pulmonary airway malformations (CPAMs) are a heterogeneous group of congenital, non-hereditary lesions of the lung, cystic and non-cystic type with clear developmental anomalies and evident malformative changes, which derive from the excessive proliferation of the tubular bronchial structures. We described two rare cases of type IV CPAM detected in adult patients with different clinical presentation: one of these cases was symptomatic, complaining of cough and hemoptysis. Conversely, the other case was reported as incidental findings in patient with abdominal pain without respiratory symptoms. Chest computed tomography (CT) scan was performed showing voluminous cystic formations with fibrotic septa within the lesions in both patients. The patient with hemoptysis was subjected to video assisted thoracoscopic lobectomy, while the other one was hospitalized to perform biopsy, which confirmed the diagnosis of CPAM. All patients were advised to follow-up. The incidence of type IV CPAM in adult patients is probably underestimated; the knowledge of the CT features of CPAM is crucial for a correct diagnosis and an appropriate management of asymptomatic patients, which may be conservative.
Lingua originaleEnglish
pagine (da-a)45-51
Numero di pagine7
RivistaMinerva Pneumologica
Volume58
Stato di pubblicazionePublished - 2019

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Lung
Hemoptysis
Tomography
Incidental Findings
Cough
Abdominal Pain
Thorax
Biopsy
Incidence

All Science Journal Classification (ASJC) codes

  • Pulmonary and Respiratory Medicine

Cita questo

Congenital pulmonary airway malformation in adult: report of two rare cases and literature review. / Albano, Domenico; Midiri, Massimo; Bartolotta, Tommaso Vincenzo; Galia, Massimo; Gagliardo, Cesare; Bruno, Alberto; Sidoti Pinto, Antonio; Leto, Claudio; Giambelluca, Dario; Cutaia, Giuseppe; Salvaggio, Giuseppe; Salvaggio, Leonardo.

In: Minerva Pneumologica, Vol. 58, 2019, pag. 45-51.

Risultato della ricerca: Article

Albano, D, Midiri, M, Bartolotta, TV, Galia, M, Gagliardo, C, Bruno, A, Sidoti Pinto, A, Leto, C, Giambelluca, D, Cutaia, G, Salvaggio, G & Salvaggio, L 2019, 'Congenital pulmonary airway malformation in adult: report of two rare cases and literature review', Minerva Pneumologica, vol. 58, pagg. 45-51.
Albano, Domenico ; Midiri, Massimo ; Bartolotta, Tommaso Vincenzo ; Galia, Massimo ; Gagliardo, Cesare ; Bruno, Alberto ; Sidoti Pinto, Antonio ; Leto, Claudio ; Giambelluca, Dario ; Cutaia, Giuseppe ; Salvaggio, Giuseppe ; Salvaggio, Leonardo. / Congenital pulmonary airway malformation in adult: report of two rare cases and literature review. In: Minerva Pneumologica. 2019 ; Vol. 58. pagg. 45-51.
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title = "Congenital pulmonary airway malformation in adult: report of two rare cases and literature review",
abstract = "Congenital pulmonary airway malformations (CPAMs) are a heterogeneous group of congenital, non-hereditary lesions of the lung, cystic and non-cystic type with clear developmental anomalies and evident malformative changes, which derive from the excessive proliferation of the tubular bronchial structures. We described two rare cases of type IV CPAM detected in adult patients with different clinical presentation: one of these cases was symptomatic, complaining of cough and hemoptysis. Conversely, the other case was reported as incidental findings in patient with abdominal pain without respiratory symptoms. Chest computed tomography (CT) scan was performed showing voluminous cystic formations with fibrotic septa within the lesions in both patients. The patient with hemoptysis was subjected to video assisted thoracoscopic lobectomy, while the other one was hospitalized to perform biopsy, which confirmed the diagnosis of CPAM. All patients were advised to follow-up. The incidence of type IV CPAM in adult patients is probably underestimated; the knowledge of the CT features of CPAM is crucial for a correct diagnosis and an appropriate management of asymptomatic patients, which may be conservative.",
author = "Domenico Albano and Massimo Midiri and Bartolotta, {Tommaso Vincenzo} and Massimo Galia and Cesare Gagliardo and Alberto Bruno and {Sidoti Pinto}, Antonio and Claudio Leto and Dario Giambelluca and Giuseppe Cutaia and Giuseppe Salvaggio and Leonardo Salvaggio",
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T1 - Congenital pulmonary airway malformation in adult: report of two rare cases and literature review

AU - Albano, Domenico

AU - Midiri, Massimo

AU - Bartolotta, Tommaso Vincenzo

AU - Galia, Massimo

AU - Gagliardo, Cesare

AU - Bruno, Alberto

AU - Sidoti Pinto, Antonio

AU - Leto, Claudio

AU - Giambelluca, Dario

AU - Cutaia, Giuseppe

AU - Salvaggio, Giuseppe

AU - Salvaggio, Leonardo

PY - 2019

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N2 - Congenital pulmonary airway malformations (CPAMs) are a heterogeneous group of congenital, non-hereditary lesions of the lung, cystic and non-cystic type with clear developmental anomalies and evident malformative changes, which derive from the excessive proliferation of the tubular bronchial structures. We described two rare cases of type IV CPAM detected in adult patients with different clinical presentation: one of these cases was symptomatic, complaining of cough and hemoptysis. Conversely, the other case was reported as incidental findings in patient with abdominal pain without respiratory symptoms. Chest computed tomography (CT) scan was performed showing voluminous cystic formations with fibrotic septa within the lesions in both patients. The patient with hemoptysis was subjected to video assisted thoracoscopic lobectomy, while the other one was hospitalized to perform biopsy, which confirmed the diagnosis of CPAM. All patients were advised to follow-up. The incidence of type IV CPAM in adult patients is probably underestimated; the knowledge of the CT features of CPAM is crucial for a correct diagnosis and an appropriate management of asymptomatic patients, which may be conservative.

AB - Congenital pulmonary airway malformations (CPAMs) are a heterogeneous group of congenital, non-hereditary lesions of the lung, cystic and non-cystic type with clear developmental anomalies and evident malformative changes, which derive from the excessive proliferation of the tubular bronchial structures. We described two rare cases of type IV CPAM detected in adult patients with different clinical presentation: one of these cases was symptomatic, complaining of cough and hemoptysis. Conversely, the other case was reported as incidental findings in patient with abdominal pain without respiratory symptoms. Chest computed tomography (CT) scan was performed showing voluminous cystic formations with fibrotic septa within the lesions in both patients. The patient with hemoptysis was subjected to video assisted thoracoscopic lobectomy, while the other one was hospitalized to perform biopsy, which confirmed the diagnosis of CPAM. All patients were advised to follow-up. The incidence of type IV CPAM in adult patients is probably underestimated; the knowledge of the CT features of CPAM is crucial for a correct diagnosis and an appropriate management of asymptomatic patients, which may be conservative.

UR - http://hdl.handle.net/10447/356449

UR - https://www.minervamedica.it/en/journals/minerva-pneumologica/article.php?cod=R16Y2019N02A0070

M3 - Article

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EP - 51

JO - Minerva Pneumologica

JF - Minerva Pneumologica

SN - 0026-4954

ER -