Concise asymmetric synthesis of Linezolid through catalyzed Henry reaction.

Andrea Pace, Antonio Palumbo Piccionello, Angela Accardo, Silvestre Buscemi, Accardo, Andrea Pace, Paola Pierro, Buscemi, A. Palumbo Piccionello, Paola Pierro

Risultato della ricerca: Articlepeer review

10 Citazioni (Scopus)


A new asymmetric synthesis of the antibiotic Linezolid was performed through a copper-catalyzed Henryreaction as the key step. The use of camphor-derived aminopyridine ligands helped to improve the yields ofthe chiral precursor and to obtain Linezolid in good overall yield and enantiomeric excess.
Lingua originaleEnglish
pagine (da-a)24946-24951
Numero di pagine6
RivistaRSC Advances
Stato di pubblicazionePublished - 2013

All Science Journal Classification (ASJC) codes

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  • ???subjectarea.asjc.1500.1500???

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