Previous research has reported that children with idiopathic short stature (ISS) showedfunctional and cognitive impairments. The purpose of this study was to compare muscle strengthand body posture between children with ISS treated with growth hormone (GH) and healthy peers(healthy children, HC), and to analyze whether these parameters were affected by physical exercise.Eighteen children for the ISS group (mean age: 10.96 ± 1.68 years) and 26 children for the HC group(mean age: 10.19 ± 1.06 years) were recruited for the study. All participants performed the followingassessments: handgrip and Sargent test for the muscle strength evaluation; baropodometric andstabilometric test for the posturographic measures. Data were analyzed with analysis of covariance(ANCOVA) using height and weight as covariate. Groups were then stratified into active andinactive and independent t-tests were used to determine differences between variables. Significancelevel was set to p < 0.05. Our results showed a significantly lower performance for both hands (p <0.01) and a greater difference of plantar loading distribution between feet in the ISS compared tothe HC groups (p < 0.01). In relation to physical exercise, the HC active group showed the highesthandgrip strength values for both hands among the analyzed groups and, moreover, handgripstrength of both ISS active and inactive groups was significantly lower than corresponding CH peersfor both hands. Although ISS and HC inactive groups reported an unequal plantar loadingdistribution between feet (p < 0.05), this asymmetry was not present in both ISS and HC activegroups. We assume that GH therapy integrated with physical exercise in young patients with ISScould be suggested to increase muscle strength and body posture improving their quality of life.
|Numero di pagine||10|
|Stato di pubblicazione||Published - 2020|
All Science Journal Classification (ASJC) codes