TY - JOUR
T1 - Comparative chemical composition and bioactivity of leaves essential oils from nine Sicilian accessions of Myrtus communis L
AU - Leto, Claudio
AU - Bruno, Maurizio
AU - Maggio, Antonella Maria
AU - Riccobono, Luana
AU - La Bella, Salvatore
AU - Tuttolomondo, Teresa
AU - Cammalleri, Ignazio
AU - Tenuta, Maria Concetta
AU - Leporini, Mariarosaria
AU - Falco, Tiziana
AU - Tundis, Rosa
AU - Loizzo, Monica Rosa
PY - 2019
Y1 - 2019
N2 - In this study, the essential oils obtained from the leaves of Myrtus communis L. stored in a collection orchard located at the experimental station ‘Orleans’ of the Department of Agricultural and Forest Sciences of the University of Palermo (Italy) were investigated. The essential oils, analysed by gas chromatography–mass spectrometry, revealed the presence of α-pinene, 1,8-cineole, linalool, limonene and myrtenyl acetate as dominant constituents. The neuroprotective effects of M. communis essential oils were investigated by analysing the antioxidant properties and cholinesterases (acetylcholinesterase, AChE, and butyrylcholinesterase, BChE) inhibitory activity. Essential oils from Scopello accession possessed a promising radical scavenging potential with IC50 values of 71.4 and 75.9 μg/mL for EO1 and EO2, respectively. Essential oil from Monte Pellegrino (EO5) showed the highest cholinesterase inhibitory activity with IC50 values of 96.0 and 87.9 μg/mL for AChE and BChE, respectively. Significant result was obtained also with EO1 against the BChE (IC50 of 77.8 μg/mL). Data on essential oil together with antioxidant effects were used as variables to set a matrix for statistical analysis. Results suggest that M. communis leaves EO could be potentially used in pharmaceutical field.
AB - In this study, the essential oils obtained from the leaves of Myrtus communis L. stored in a collection orchard located at the experimental station ‘Orleans’ of the Department of Agricultural and Forest Sciences of the University of Palermo (Italy) were investigated. The essential oils, analysed by gas chromatography–mass spectrometry, revealed the presence of α-pinene, 1,8-cineole, linalool, limonene and myrtenyl acetate as dominant constituents. The neuroprotective effects of M. communis essential oils were investigated by analysing the antioxidant properties and cholinesterases (acetylcholinesterase, AChE, and butyrylcholinesterase, BChE) inhibitory activity. Essential oils from Scopello accession possessed a promising radical scavenging potential with IC50 values of 71.4 and 75.9 μg/mL for EO1 and EO2, respectively. Essential oil from Monte Pellegrino (EO5) showed the highest cholinesterase inhibitory activity with IC50 values of 96.0 and 87.9 μg/mL for AChE and BChE, respectively. Significant result was obtained also with EO1 against the BChE (IC50 of 77.8 μg/mL). Data on essential oil together with antioxidant effects were used as variables to set a matrix for statistical analysis. Results suggest that M. communis leaves EO could be potentially used in pharmaceutical field.
KW - Myrtus communis
KW - antioxidant activity
KW - chemical profile
KW - cholinesterase inhibitory activity
KW - leaves
KW - Myrtus communis
KW - antioxidant activity
KW - chemical profile
KW - cholinesterase inhibitory activity
KW - leaves
UR - http://hdl.handle.net/10447/392405
UR - http://www.tandfonline.com/toc/tjeo20/current
M3 - Article
VL - 31
SP - 546
EP - 555
JO - Journal of Essential Oil Research
JF - Journal of Essential Oil Research
SN - 1041-2905
ER -