Comparative bench study evaluation of different infant interfaces for non-invasive ventilation

Cesare Gregoretti, Andrea Cortegiani, Giorgia Spinazzola, Olimpia Festa, Giorgio Conti, Giuliano Ferrone, Luca Tortorolo, Marco Piastra, Roberta Costa

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Abstract

Background: To compare, in terms of patient-ventilator interaction and performance, a new nasal mask (Respireo, AirLiquide, FR) with the Endotracheal tube (ET) and a commonly used nasal mask (FPM, Fisher and Paykel, NZ) for delivering Pressure Support Ventilation (PSV) in an infant model of Acute Respiratory Failure (ARF). Methods: An active test lung (ASL 5000) connected to an infant mannequin through 3 different interfaces (Respireo, ET and FPM), was ventilated with a standard ICU ventilator set in PSV. The test lung was set to simulate a 5.5 kg infant with ARF, breathing at 50 and 60 breaths/min). Non-invasive ventilation (NIV) mode was not used and the leaks were nearly zero. Results: The ET showed the shortest inspiratory trigger delay and pressurization time compared to FPM and Respireo (p < 0.01). At each respiratory rate tested, the FPM showed the shortest Expiratory trigger delay compared to ET and Respireo (p < 0.01). The Respireo presented a lower value of Inspiratory pressure-time product and trigger pressure drop than ET (p < 0.01), while no significant difference was found in terms of pressure-time product at 300 and 500 ms. During all tests, compared with the FPM, ET showed a significantly higher tidal volume (VT) delivered (p < 0.01), while Respireo showed a trend toward an increase of tidal volume delivered compared with FPM. Conclusions: The ET showed a better patient-ventilator interaction and performance compared to both the nasal masks. Despite the higher internal volume, Respireo showed a trend toward an increase of the delivered tidal volume; globally, its efficiency in terms of patient-ventilator interaction was comparable to the FPM, which is the infant NIV mask characterized by the smaller internal volume among the (few) models on the market.
Lingua originaleEnglish
pagine (da-a)57-
Numero di pagine8
RivistaBMC Pulmonary Medicine
Volume18
Stato di pubblicazionePublished - 2018

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All Science Journal Classification (ASJC) codes

  • Pulmonary and Respiratory Medicine

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Gregoretti, C., Cortegiani, A., Spinazzola, G., Festa, O., Conti, G., Ferrone, G., Tortorolo, L., Piastra, M., & Costa, R. (2018). Comparative bench study evaluation of different infant interfaces for non-invasive ventilation. BMC Pulmonary Medicine, 18, 57-.