Abstract
| Lingua originale | English |
|---|---|
| pagine (da-a) | 791-795 |
| Numero di pagine | 5 |
| Rivista | Default journal |
| Volume | 31 |
| Stato di pubblicazione | Published - 2017 |
Fingerprint
All Science Journal Classification (ASJC) codes
- Endocrinology, Diabetes and Metabolism
- Immunology and Allergy
- Physiology
- Immunology
- Oncology
- Endocrinology
- Physiology (medical)
- Cancer Research
Cita questo
COLORECTAL CANCER AND INFLAMMATORY BOWEL DISEASES: EFFECTS ON DIET AND ANTIOXIDANTS. / Tomasello, Giovanni; Carini, Francesco; Cappello, Francesco; David, Sabrina; Leone, Angelo; Sinagra, Emanuele; Geagea, Alice Gerges; Mazzola, Margherita; Kattar; Jurjus.
In: Default journal, Vol. 31, 2017, pag. 791-795.Risultato della ricerca: Article
}
TY - JOUR
T1 - COLORECTAL CANCER AND INFLAMMATORY BOWEL DISEASES: EFFECTS ON DIET AND ANTIOXIDANTS
AU - Tomasello, Giovanni
AU - Carini, Francesco
AU - Cappello, Francesco
AU - David, Sabrina
AU - Leone, Angelo
AU - Sinagra, Emanuele
AU - Geagea, Alice Gerges
AU - Mazzola, Margherita
AU - Kattar, null
AU - Jurjus, null
PY - 2017
Y1 - 2017
N2 - It is well established that oxidative stress is common in inflammatory bowel diseases (IBDs). Accordingly, antioxidants are recommended for treatment. The aim of this is to compare the effects of antioxidants contained in the various types of tea on symptoms and evolution of IBD and colorectal cancer (CRC). Analysis of the literature revealed that the theaflavin-3, 30-digitale (TFDG) contained in black tea, and epigallocatechin-3-0-gallate (EGCG) contained in green tea have protective effects against oxidative stress. Moreover, these substances are involved in many biochemical processes responsible for inflammation and proliferation of cancer cells. It is documented that both TFDG and EGCG are able to reduce inflammatory phenomena and sympotms associated with IBD, as well as to reduce the proliferation of CRC cells. Most studies are performed in vitro or in experimental animal models. It is, therefore, advisable to formulate studies that could be carried out on humans or human samples, in order to develop the appropriate therapeutic strategies.
AB - It is well established that oxidative stress is common in inflammatory bowel diseases (IBDs). Accordingly, antioxidants are recommended for treatment. The aim of this is to compare the effects of antioxidants contained in the various types of tea on symptoms and evolution of IBD and colorectal cancer (CRC). Analysis of the literature revealed that the theaflavin-3, 30-digitale (TFDG) contained in black tea, and epigallocatechin-3-0-gallate (EGCG) contained in green tea have protective effects against oxidative stress. Moreover, these substances are involved in many biochemical processes responsible for inflammation and proliferation of cancer cells. It is documented that both TFDG and EGCG are able to reduce inflammatory phenomena and sympotms associated with IBD, as well as to reduce the proliferation of CRC cells. Most studies are performed in vitro or in experimental animal models. It is, therefore, advisable to formulate studies that could be carried out on humans or human samples, in order to develop the appropriate therapeutic strategies.
UR - http://hdl.handle.net/10447/243373
M3 - Article
VL - 31
SP - 791
EP - 795
JO - Default journal
JF - Default journal
ER -