COLORECTAL CANCER: AN UPDATE ON THE EFFECTS OF LYCOPENE ON TUMOR PROGRESSION AND CELL PROLIFERATION

Giovanni Tomasello, Francesca Rappa, Sabrina David, Angelo Leone, Francesco Cappello, Francesco Carini, Rosalyn Jurjus, Battaglia, Rappa, Margherita Mazzola, Alice Gerges Geagea, Tomasello, Jurjus, Cappello

Risultato della ricerca: Article

8 Citazioni (Scopus)

Abstract

Colorectal cancer (CRC) is one of the most common cancers worldwide. Various factors, including oxidative stress, where excessive productions of reactive oxygen species (ROS) and reactive nitrogen species (RNS) occur, contribute to its pathogenesis. Numerous studies have investigated the effect of antioxidant substances derived from food such fruits and vegetables; however, data on Lycopene are still rare. Stidies on HT-29 colorectal cancer cells and on animal models have shown that Lycopene has effects on cell proliferation and on the progression of the CRC by interacting with variuos cellular signaling pathways. this analysis of the literature focused on the antioxidant effect of Lycopene, a substance that is found in the tomato.
Lingua originaleEnglish
pagine (da-a)774-796
Numero di pagine23
RivistaJOURNAL OF BIOLOGICAL REGULATORS & HOMEOSTATIC AGENTS
Volume31
Stato di pubblicazionePublished - 2017

Fingerprint

Colorectal Neoplasms
Cell Proliferation
Antioxidants
Reactive Nitrogen Species
Neoplasms
Lycopersicon esculentum
Vegetables
Reactive Oxygen Species
Fruit
Oxidative Stress
Animal Models
Food
lycopene

All Science Journal Classification (ASJC) codes

  • Endocrinology, Diabetes and Metabolism
  • Immunology and Allergy
  • Physiology
  • Immunology
  • Oncology
  • Endocrinology
  • Physiology (medical)
  • Cancer Research

Cita questo

COLORECTAL CANCER: AN UPDATE ON THE EFFECTS OF LYCOPENE ON TUMOR PROGRESSION AND CELL PROLIFERATION. / Tomasello, Giovanni; Rappa, Francesca; David, Sabrina; Leone, Angelo; Cappello, Francesco; Carini, Francesco; Jurjus, Rosalyn; Battaglia; Rappa; Mazzola, Margherita; Gerges Geagea, Alice; Tomasello; Jurjus; Cappello.

In: JOURNAL OF BIOLOGICAL REGULATORS & HOMEOSTATIC AGENTS, Vol. 31, 2017, pag. 774-796.

Risultato della ricerca: Article

@article{64f8176f688546c5aaa36a92dc48b4fe,
title = "COLORECTAL CANCER: AN UPDATE ON THE EFFECTS OF LYCOPENE ON TUMOR PROGRESSION AND CELL PROLIFERATION",
abstract = "Colorectal cancer (CRC) is one of the most common cancers worldwide. Various factors, including oxidative stress, where excessive productions of reactive oxygen species (ROS) and reactive nitrogen species (RNS) occur, contribute to its pathogenesis. Numerous studies have investigated the effect of antioxidant substances derived from food such fruits and vegetables; however, data on Lycopene are still rare. Stidies on HT-29 colorectal cancer cells and on animal models have shown that Lycopene has effects on cell proliferation and on the progression of the CRC by interacting with variuos cellular signaling pathways. this analysis of the literature focused on the antioxidant effect of Lycopene, a substance that is found in the tomato.",
author = "Giovanni Tomasello and Francesca Rappa and Sabrina David and Angelo Leone and Francesco Cappello and Francesco Carini and Rosalyn Jurjus and Battaglia and Rappa and Margherita Mazzola and {Gerges Geagea}, Alice and Tomasello and Jurjus and Cappello",
year = "2017",
language = "English",
volume = "31",
pages = "774--796",
journal = "JOURNAL OF BIOLOGICAL REGULATORS & HOMEOSTATIC AGENTS",
issn = "0393-974X",

}

TY - JOUR

T1 - COLORECTAL CANCER: AN UPDATE ON THE EFFECTS OF LYCOPENE ON TUMOR PROGRESSION AND CELL PROLIFERATION

AU - Tomasello, Giovanni

AU - Rappa, Francesca

AU - David, Sabrina

AU - Leone, Angelo

AU - Cappello, Francesco

AU - Carini, Francesco

AU - Jurjus, Rosalyn

AU - Battaglia, null

AU - Rappa, null

AU - Mazzola, Margherita

AU - Gerges Geagea, Alice

AU - Tomasello, null

AU - Jurjus, null

AU - Cappello, null

PY - 2017

Y1 - 2017

N2 - Colorectal cancer (CRC) is one of the most common cancers worldwide. Various factors, including oxidative stress, where excessive productions of reactive oxygen species (ROS) and reactive nitrogen species (RNS) occur, contribute to its pathogenesis. Numerous studies have investigated the effect of antioxidant substances derived from food such fruits and vegetables; however, data on Lycopene are still rare. Stidies on HT-29 colorectal cancer cells and on animal models have shown that Lycopene has effects on cell proliferation and on the progression of the CRC by interacting with variuos cellular signaling pathways. this analysis of the literature focused on the antioxidant effect of Lycopene, a substance that is found in the tomato.

AB - Colorectal cancer (CRC) is one of the most common cancers worldwide. Various factors, including oxidative stress, where excessive productions of reactive oxygen species (ROS) and reactive nitrogen species (RNS) occur, contribute to its pathogenesis. Numerous studies have investigated the effect of antioxidant substances derived from food such fruits and vegetables; however, data on Lycopene are still rare. Stidies on HT-29 colorectal cancer cells and on animal models have shown that Lycopene has effects on cell proliferation and on the progression of the CRC by interacting with variuos cellular signaling pathways. this analysis of the literature focused on the antioxidant effect of Lycopene, a substance that is found in the tomato.

UR - http://hdl.handle.net/10447/243404

M3 - Article

VL - 31

SP - 774

EP - 796

JO - JOURNAL OF BIOLOGICAL REGULATORS & HOMEOSTATIC AGENTS

JF - JOURNAL OF BIOLOGICAL REGULATORS & HOMEOSTATIC AGENTS

SN - 0393-974X

ER -