Multiple Sclerosis (MS) is characterized by motor, cognitive, and neuropsychiatric symptoms, which can occurindependently.While MS is traditionally considered an inflammatory disease of the white matter, degeneration of gray matter is increasinglyrecognized as an important contributor to the progressive cognitive decline. A protective factor against the progressionof cognitive dysfunction in MS could be the cognitive reserve, defined as resistance to brain dysfunction.Aim of the present study is to evaluate the role of cognitive reserve for different aspects of cognitive dysfunctionof patients with MS.We found that patients with MS and lower cognitive reserve have poorer neuropsychological performance andslower information speed processing.These findings support the notion that intellectual reserve may protect some aspects of cognitive function inpatients with MS.
|Numero di pagine||6|
|Rivista||Archives Italiennes de Biologie|
|Stato di pubblicazione||Published - 2015|
All Science Journal Classification (ASJC) codes