TY - JOUR
T1 - Cognitive processess and cognitive reservein multiple sclerosis
AU - Scalera, Cinzia
AU - Chillemi, Gaetana
AU - Chillemi, null
AU - Terranova, null
AU - Calamuneri, Alessandro
AU - Scalera, null
AU - Rizzo, null
AU - Bruschetta, null
AU - Dattola, null
AU - Buccafusca, Maria
AU - Quartarone, Angelo
AU - Girlanda, Paolo
AU - Dattola, Vincenzo
AU - Rizzo, Vincenzo
PY - 2015
Y1 - 2015
N2 - Multiple Sclerosis (MS) is characterized by motor, cognitive, and neuropsychiatric symptoms, which can occurindependently.While MS is traditionally considered an inflammatory disease of the white matter, degeneration of gray matter is increasinglyrecognized as an important contributor to the progressive cognitive decline. A protective factor against the progressionof cognitive dysfunction in MS could be the cognitive reserve, defined as resistance to brain dysfunction.Aim of the present study is to evaluate the role of cognitive reserve for different aspects of cognitive dysfunctionof patients with MS.We found that patients with MS and lower cognitive reserve have poorer neuropsychological performance andslower information speed processing.These findings support the notion that intellectual reserve may protect some aspects of cognitive function inpatients with MS.
AB - Multiple Sclerosis (MS) is characterized by motor, cognitive, and neuropsychiatric symptoms, which can occurindependently.While MS is traditionally considered an inflammatory disease of the white matter, degeneration of gray matter is increasinglyrecognized as an important contributor to the progressive cognitive decline. A protective factor against the progressionof cognitive dysfunction in MS could be the cognitive reserve, defined as resistance to brain dysfunction.Aim of the present study is to evaluate the role of cognitive reserve for different aspects of cognitive dysfunctionof patients with MS.We found that patients with MS and lower cognitive reserve have poorer neuropsychological performance andslower information speed processing.These findings support the notion that intellectual reserve may protect some aspects of cognitive function inpatients with MS.
KW - Multiple sclerosis • Cognitive Reserve • Verbal cognitive processes • Visual-space processes
KW - Multiple sclerosis • Cognitive Reserve • Verbal cognitive processes • Visual-space processes
UR - http://hdl.handle.net/10447/220608
M3 - Article
SN - 0003-9829
VL - 153
SP - 19
EP - 24
JO - Archives Italiennes de Biologie
JF - Archives Italiennes de Biologie
ER -