Co-Registering Kinematics and Evoked Related Potentials during Visually Guided Reach-to-Grasp Movements

Vincenza Tarantino, Chiara Begliomini, Vincenza Tarantino, Teresa De Sanctis, Elisa Straulino, Umberto Castiello

Risultato della ricerca: Article

7 Citazioni (Scopus)

Abstract

Background:In non-human primates grasp-related sensorimotor transformations are accomplished in a circuit involving the anterior intraparietal sulcus (area AIP) and both the ventral and the dorsal sectors of the premotor cortex (vPMC and dPMC, respectively). Although a human homologue of such a circuit has been identified, the time course of activation of these cortical areas and how such activity relates to specific kinematic events has yet to be investigated.Methodology/Principal Findings:We combined kinematic and event-related potential techniques to explicitly test how activity within human grasping-related brain areas is modulated in time. Subjects were requested to reach towards and grasp either a small stimulus using a precision grip (i.e., the opposition of index finger and thumb) or a large stimulus using a whole hand grasp (i.e., the flexion of all digits around the stimulus). Results revealed a time course of activation starting at the level of parietal regions and continuing at the level of premotor regions. More specifically, we show that activity within these regions was tuned for specific grasps well before movement onset and this early tuning was carried over - as evidenced by kinematic analysis - during the preshaping period of the task.Conclusions/Significance:Data are discussed in terms of recent findings showing a marked differentiation across different grasps during premovement phases which was carried over into subsequent movement phases. These findings offer a substantial contribution to the current debate about the nature of the sensorimotor transformations underlying grasping. And provide new insights into the detailed movement information contained in the human preparatory activity for specific hand movements. © 2013 De Sanctis et al.
Lingua originaleEnglish
Numero di pagine0
RivistaPLoS One
Volume8
Stato di pubblicazionePublished - 2013

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Hand Strength
kinematics
Evoked Potentials
Biomechanical Phenomena
Kinematics
hands
Chemical activation
Parietal Lobe
Networks (circuits)
Human Activities
Brain
cortex
Primates
Hand
Tuning
brain
Thumb
Motor Cortex
methodology
Fingers

All Science Journal Classification (ASJC) codes

  • Biochemistry, Genetics and Molecular Biology(all)
  • Agricultural and Biological Sciences(all)
  • General

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Tarantino, V., Begliomini, C., Tarantino, V., De Sanctis, T., Straulino, E., & Castiello, U. (2013). Co-Registering Kinematics and Evoked Related Potentials during Visually Guided Reach-to-Grasp Movements. PLoS One, 8.

Co-Registering Kinematics and Evoked Related Potentials during Visually Guided Reach-to-Grasp Movements. / Tarantino, Vincenza; Begliomini, Chiara; Tarantino, Vincenza; De Sanctis, Teresa; Straulino, Elisa; Castiello, Umberto.

In: PLoS One, Vol. 8, 2013.

Risultato della ricerca: Article

Tarantino, V, Begliomini, C, Tarantino, V, De Sanctis, T, Straulino, E & Castiello, U 2013, 'Co-Registering Kinematics and Evoked Related Potentials during Visually Guided Reach-to-Grasp Movements', PLoS One, vol. 8.
Tarantino, Vincenza ; Begliomini, Chiara ; Tarantino, Vincenza ; De Sanctis, Teresa ; Straulino, Elisa ; Castiello, Umberto. / Co-Registering Kinematics and Evoked Related Potentials during Visually Guided Reach-to-Grasp Movements. In: PLoS One. 2013 ; Vol. 8.
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