Clinical utility of novel biomarkers for cardiovascular disease risk stratification

Maurizio Averna, Davide Noto

Risultato della ricerca: Articlepeer review

4 Citazioni (Scopus)

Abstract

Over the past few decades, a number of coronary artery disease (CAD) and cardiovascular disease (CVD) risk factors have been identified. The predictive power of "conventional" risk factors have been validated by observational, prospective and intervention studies. Nevertheless, all attempts to exactly predict the individual risk for CAD have failed, biased by a large number of incorrectly risk-classified subjects. To improve cardiovascular (CV) risk prediction, a large number of genetic and/or non-genetic biomarkers have been discovered and tested against the "classical" risk factors for their power to predict CV risk. Only few of them had a significant improvement over the predictive models. In this paper, the most investigated biomarkers will be discussed and the evidence of their use as predictors of CV will be questioned.
Lingua originaleEnglish
pagine (da-a)263-270
Numero di pagine8
RivistaInternal and Emergency Medicine
Volume7
Stato di pubblicazionePublished - 2012

All Science Journal Classification (ASJC) codes

  • Internal Medicine
  • Emergency Medicine

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