Clinical-anatomical correlation in a selective phonemic speech production impairment

Lisa Cipolotti, Larner, Muqit, Rakshi, Kartsounis, Lisa Cipolotti, Martin N. Rossor, Gail Robinson, Wise

Risultato della ricerca: Articlepeer review

9 Citazioni (Scopus)


Although phonemic paraphasias are common in aphasic disorders, including Broca's aphasia, conduction aphasia and transcortical motor aphasia, selective phonemic speech production impairment, or phonemic disintegration, is unusual. A patient with a selective phonemic speech production disorder underwent clinical, neuropsychological and structural neuroradiological assessment over a period of 6 years. The disorder was characterised by phonemic paraphasias (phonemic disintegration) with preserved comprehension and naming. Imaging showed a focal lesion in the white matter of the left precentral gyrus and, to a lesser extent, the posterior part of the left middle frontal gyrus, with overlying cortical atrophy. Biopsy of the lesion, after several years of observation, showed a calcified haemangioma. Clinical-anatomical correlation in this case suggests the importance of primary motor cortex of the inferior precentral (pre-Rolandic) gyrus and subjacent white matter in phoneme production, with sparing of the posterior inferior frontal gyrus (Broca's area).
Lingua originaleEnglish
pagine (da-a)23-29
Numero di pagine7
RivistaJournal of the Neurological Sciences
Volume219 Apr (1-2)
Stato di pubblicazionePublished - 2004

All Science Journal Classification (ASJC) codes

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  • ???subjectarea.asjc.2700.2728???


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