Chloroquine for COVID-19: rationale, facts, hopes

Andrea Cortegiani; Sharon Einav; Giulia Ingoglia; Mariachiara Ippolito

Chloroquine for COVID-19: rationale, facts, hopes

Andrea Cortegiani, Sharon Einav, Giulia Ingoglia, Mariachiara Ippolito

Discipline Chirurgiche, Oncologiche e Stomatologiche

Risultato della ricerca: Article › peer review

12 Citazioni (Scopus)

Abstract

The tragedy of the pandemic coronavirus disease 2019(COVID-19) led to a desperate search for effective treatments. Chloroquine (CQ), an aminoquinoline used formany years for the prophylaxis and therapy of malariaand autoimmune diseases, has been put forward as atreatment option.The fact that CQ is not patented and has been in clinical use for years is a major advantage. CQ has beenshown to have antiviral effects in SARS, MERS, Ebola,and HIV infections, but without data showing clinical effectiveness [1, 2]. Does the current level of evidence suffice for prescribing CQ for COVID-19?

Lingua originale	English
Numero di pagine	3
Rivista	Critical Care
Volume	24
Stato di pubblicazione	Published - 2020

All Science Journal Classification (ASJC) codes

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abstract = "The tragedy of the pandemic coronavirus disease 2019(COVID-19) led to a desperate search for effective treatments. Chloroquine (CQ), an aminoquinoline used formany years for the prophylaxis and therapy of malariaand autoimmune diseases, has been put forward as atreatment option.The fact that CQ is not patented and has been in clinical use for years is a major advantage. CQ has beenshown to have antiviral effects in SARS, MERS, Ebola,and HIV infections, but without data showing clinical effectiveness [1, 2]. Does the current level of evidence suffice for prescribing CQ for COVID-19?",

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AU - Cortegiani, Andrea

AU - Einav, Sharon

AU - Ingoglia, Giulia

AU - Ippolito, Mariachiara

PY - 2020

Y1 - 2020

N2 - The tragedy of the pandemic coronavirus disease 2019(COVID-19) led to a desperate search for effective treatments. Chloroquine (CQ), an aminoquinoline used formany years for the prophylaxis and therapy of malariaand autoimmune diseases, has been put forward as atreatment option.The fact that CQ is not patented and has been in clinical use for years is a major advantage. CQ has beenshown to have antiviral effects in SARS, MERS, Ebola,and HIV infections, but without data showing clinical effectiveness [1, 2]. Does the current level of evidence suffice for prescribing CQ for COVID-19?

AB - The tragedy of the pandemic coronavirus disease 2019(COVID-19) led to a desperate search for effective treatments. Chloroquine (CQ), an aminoquinoline used formany years for the prophylaxis and therapy of malariaand autoimmune diseases, has been put forward as atreatment option.The fact that CQ is not patented and has been in clinical use for years is a major advantage. CQ has beenshown to have antiviral effects in SARS, MERS, Ebola,and HIV infections, but without data showing clinical effectiveness [1, 2]. Does the current level of evidence suffice for prescribing CQ for COVID-19?

UR - http://hdl.handle.net/10447/415537

M3 - Article

SN - 1364-8535

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JO - Critical Care

JF - Critical Care

ER -

Chloroquine for COVID-19: rationale, facts, hopes

Abstract

All Science Journal Classification (ASJC) codes

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