Abstract
| Lingua originale | English |
|---|---|
| pagine (da-a) | 1715-1724 |
| Numero di pagine | 10 |
| Rivista | ACS BIOMATERIALS SCIENCE & ENGINEERING |
| Volume | 5 |
| Stato di pubblicazione | Published - 2019 |
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All Science Journal Classification (ASJC) codes
- Biomaterials
- Biomedical Engineering
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Chitosan-Coating Deposition via Galvanic Coupling. / Carfi' Pavia, Francesco; Sunseri, Carmelo; La Carrubba, Vincenzo; Conoscenti, Gioacchino; Brucato, Valerio Maria Bartolo; Piazza, Salvatore; Inguanta, Rosalinda; Conoscenti, Gioacchino; La Carrubba, Vincenzo; Brucato, Valerio; Blanda, Giuseppe.
In: ACS BIOMATERIALS SCIENCE & ENGINEERING, Vol. 5, 2019, pag. 1715-1724.Risultato della ricerca: Article
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TY - JOUR
T1 - Chitosan-Coating Deposition via Galvanic Coupling
AU - Carfi' Pavia, Francesco
AU - Sunseri, Carmelo
AU - La Carrubba, Vincenzo
AU - Conoscenti, Gioacchino
AU - Brucato, Valerio Maria Bartolo
AU - Piazza, Salvatore
AU - Inguanta, Rosalinda
AU - Conoscenti, Gioacchino
AU - La Carrubba, Vincenzo
AU - Brucato, Valerio
AU - Blanda, Giuseppe
PY - 2019
Y1 - 2019
N2 - A galvanic method to deposit chitosan coatings on stainless steel substrate is reported. Deposition of suitable coatings is desired to improve biocompatibility and corrosion resistance of metallic medical devices to be implanted in human body. In the present work, a thin hydrogel layer of chitosan was deposited on 304SS by a galvanic displacement reaction, which is advantageous first as it does not require external power supply. 304SS was immersed into an aqueous solution of chitosan/lactic acid and electrochemically coupled with magnesium acting as a sacrificial anode. SEM images showed the formation of a uniform layer of chitosan with a thickness controlled by deposition time. Corrosion tests in simulating body fluid showed that chitosan coatings shift the corrosion potential of 304 substrates toward nobler values. Finally, the cytotoxicity of the coating was investigated through cell viability assays with osteoblastic cell MC3T3-E1. The results revealed highly satisfying biocompatibility of the coating.
AB - A galvanic method to deposit chitosan coatings on stainless steel substrate is reported. Deposition of suitable coatings is desired to improve biocompatibility and corrosion resistance of metallic medical devices to be implanted in human body. In the present work, a thin hydrogel layer of chitosan was deposited on 304SS by a galvanic displacement reaction, which is advantageous first as it does not require external power supply. 304SS was immersed into an aqueous solution of chitosan/lactic acid and electrochemically coupled with magnesium acting as a sacrificial anode. SEM images showed the formation of a uniform layer of chitosan with a thickness controlled by deposition time. Corrosion tests in simulating body fluid showed that chitosan coatings shift the corrosion potential of 304 substrates toward nobler values. Finally, the cytotoxicity of the coating was investigated through cell viability assays with osteoblastic cell MC3T3-E1. The results revealed highly satisfying biocompatibility of the coating.
KW - 304SS stainless steel
KW - Biomaterials
KW - Biomedical Engineering
KW - biocoatings
KW - chitosan
KW - cytotoxicity
KW - galvanic deposition
KW - medical devices biomaterial
UR - http://hdl.handle.net/10447/352962
UR - http://pubs.acs.org/journal/abseba
M3 - Article
VL - 5
SP - 1715
EP - 1724
JO - ACS BIOMATERIALS SCIENCE & ENGINEERING
JF - ACS BIOMATERIALS SCIENCE & ENGINEERING
SN - 2373-9878
ER -