Chemistry and functional properties in prevention of neurodegenerative disorders of five Cistus species essential oils

Maurizio Bruno, Mariem Ben Jemia, Rosa Tundis, Francesco Menichini, Felice Senatore, Monica Rosa Loizzo

Risultato della ricerca: Articlepeer review

56 Citazioni (Scopus)

Abstract

The chemical composition of Cistus creticus, Cistus salvifolius, Cistus libanotis, Cistus monspeliensis and Cistus villosus essential oils has been examined by GC and GC-MS analysis. Height-nine constituents were identified in C. salvifolius oil, sixty in C. creticus, fifty-six in C. libanotis, fifty-four in C. villosus, forty-five in C. monspeliensis. Although the five species belong to the same genus, the composition showed interesting differences. Essential oils were screened also for their potential antioxidant effects (by DPPH, ABTS, FRAP and β-carotene bleaching test) and their acetylcholinesterase (AChE) and butyrylcholinesterase (BChE) inhibitory activity, useful for prevention and treatment of Alzheimer's disease. C. monspeliensis exhibited the most promising activity in β-carotene bleaching test (IC50 of 54.7μg/mL). In FRAP test C. libanotis showed a value of 19.2μM Fe(II)/g. C. salvifolius showed the highest activity against AChE (IC50 of 58.1μg/mL) while C. libanotis, C. creticus, C. salvifolius demonstrated a good inhibitory activity against BChE with IC50 values of 23.7, 29.1 and 34.2μg/mL, respectively. Overall our results could promote the use of the essential oil of different Cistus species as food additives and for formulation of herbal infusion or nutraceutical products
Lingua originaleEnglish
pagine (da-a)586-594
Numero di pagine9
RivistaFood and Chemical Toxicology
Volume59
Stato di pubblicazionePublished - 2013

All Science Journal Classification (ASJC) codes

  • Food Science
  • Toxicology

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