Characterization of PLLA scaffolds for biomedical applications

Valerio Maria Bartolo Brucato, Vincenzo La Carrubba, Francesco Carfi' Pavia, Gianluca Turco, Simona Maria Fiorentino, Michela Abrami, Mario Grassi, Gabriele Grassi, Rossella Farra

Risultato della ricerca: Article

3 Citazioni (Scopus)

Abstract

The porosity and pore size distribution of three-dimensional scaffolds have direct implications on their biomedical applications (tissue engineering, drug delivery, and wound dressing). Accordingly, in this paper, a fast, facile, and conservative method relying on low-field nuclear magnetic resonance (LF-NMR) for the evaluation of mean pore size and pore size distribution of polymeric scaffolds is reported. The applicability of the technique is demonstrated on poly-L-lactic acid scaffolds fabricated using the thermal induced phase separation. Results obtained through LF-NMR are successfully compared to scanning electron microscope and X-ray microcomputed tomography micrographs
Lingua originaleEnglish
pagine (da-a)469-477
Numero di pagine9
RivistaInternational Journal of Polymeric Materials
Volume66
Stato di pubblicazionePublished - 2017

All Science Journal Classification (ASJC) codes

  • Analytical Chemistry
  • Chemical Engineering(all)
  • Polymers and Plastics

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