Characterization of PLLA scaffolds for biomedical applications

Valerio Maria Bartolo Brucato; Vincenzo La Carrubba; Francesco Carfi' Pavia; Gianluca Turco; Simona Maria Fiorentino; Michela Abrami; Mario Grassi; Gabriele Grassi; Rossella Farra

Characterization of PLLA scaffolds for biomedical applications

Valerio Maria Bartolo Brucato, Vincenzo La Carrubba, Francesco Carfi' Pavia, Gianluca Turco, Simona Maria Fiorentino, Michela Abrami, Mario Grassi, Gabriele Grassi, Rossella Farra

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3 Citazioni (Scopus)

Abstract

The porosity and pore size distribution of three-dimensional scaffolds have direct implications on their biomedical applications (tissue engineering, drug delivery, and wound dressing). Accordingly, in this paper, a fast, facile, and conservative method relying on low-field nuclear magnetic resonance (LF-NMR) for the evaluation of mean pore size and pore size distribution of polymeric scaffolds is reported. The applicability of the technique is demonstrated on poly-L-lactic acid scaffolds fabricated using the thermal induced phase separation. Results obtained through LF-NMR are successfully compared to scanning electron microscope and X-ray microcomputed tomography micrographs

Lingua originale	English
pagine (da-a)	469-477
Numero di pagine	9
Rivista	International Journal of Polymeric Materials
Volume	66
Stato di pubblicazione	Published - 2017

All Science Journal Classification (ASJC) codes

Analytical Chemistry
Chemical Engineering(all)
Polymers and Plastics

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title = "Characterization of PLLA scaffolds for biomedical applications",

abstract = "The porosity and pore size distribution of three-dimensional scaffolds have direct implications on their biomedical applications (tissue engineering, drug delivery, and wound dressing). Accordingly, in this paper, a fast, facile, and conservative method relying on low-field nuclear magnetic resonance (LF-NMR) for the evaluation of mean pore size and pore size distribution of polymeric scaffolds is reported. The applicability of the technique is demonstrated on poly-L-lactic acid scaffolds fabricated using the thermal induced phase separation. Results obtained through LF-NMR are successfully compared to scanning electron microscope and X-ray microcomputed tomography micrographs",

author = "Brucato, {Valerio Maria Bartolo} and {La Carrubba}, Vincenzo and {Carfi' Pavia}, Francesco and Gianluca Turco and Fiorentino, {Simona Maria} and Michela Abrami and Mario Grassi and Gabriele Grassi and Rossella Farra",

year = "2017",

language = "English",

volume = "66",

pages = "469--477",

journal = "International Journal of Polymeric Materials and Polymeric Biomaterials",

issn = "0091-4037",

publisher = "Taylor and Francis Ltd.",

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TY - JOUR

T1 - Characterization of PLLA scaffolds for biomedical applications

AU - Brucato, Valerio Maria Bartolo

AU - La Carrubba, Vincenzo

AU - Carfi' Pavia, Francesco

AU - Turco, Gianluca

AU - Fiorentino, Simona Maria

AU - Abrami, Michela

AU - Grassi, Mario

AU - Grassi, Gabriele

AU - Farra, Rossella

PY - 2017

Y1 - 2017

N2 - The porosity and pore size distribution of three-dimensional scaffolds have direct implications on their biomedical applications (tissue engineering, drug delivery, and wound dressing). Accordingly, in this paper, a fast, facile, and conservative method relying on low-field nuclear magnetic resonance (LF-NMR) for the evaluation of mean pore size and pore size distribution of polymeric scaffolds is reported. The applicability of the technique is demonstrated on poly-L-lactic acid scaffolds fabricated using the thermal induced phase separation. Results obtained through LF-NMR are successfully compared to scanning electron microscope and X-ray microcomputed tomography micrographs

AB - The porosity and pore size distribution of three-dimensional scaffolds have direct implications on their biomedical applications (tissue engineering, drug delivery, and wound dressing). Accordingly, in this paper, a fast, facile, and conservative method relying on low-field nuclear magnetic resonance (LF-NMR) for the evaluation of mean pore size and pore size distribution of polymeric scaffolds is reported. The applicability of the technique is demonstrated on poly-L-lactic acid scaffolds fabricated using the thermal induced phase separation. Results obtained through LF-NMR are successfully compared to scanning electron microscope and X-ray microcomputed tomography micrographs

UR - http://hdl.handle.net/10447/260295

UR - http://www.tandf.co.uk/journals/titles/00914037.asp

M3 - Article

VL - 66

SP - 469

EP - 477

JO - International Journal of Polymeric Materials and Polymeric Biomaterials

JF - International Journal of Polymeric Materials and Polymeric Biomaterials

SN - 0091-4037

ER -