Characterization of PLLA scaffolds for biomedical applications

Valerio Maria Bartolo Brucato, Vincenzo La Carrubba, Francesco Carfi' Pavia, Gabriele Grassi, Rossella Farra, Gianluca Turco, Simona Maria Fiorentino, Michela Abrami, Mario Grassi

    Risultato della ricerca: Articlepeer review

    4 Citazioni (Scopus)

    Abstract

    The porosity and pore size distribution of three-dimensional scaffolds have direct implications on their biomedical applications (tissue engineering, drug delivery, and wound dressing). Accordingly, in this paper, a fast, facile, and conservative method relying on low-field nuclear magnetic resonance (LF-NMR) for the evaluation of mean pore size and pore size distribution of polymeric scaffolds is reported. The applicability of the technique is demonstrated on poly-L-lactic acid scaffolds fabricated using the thermal induced phase separation. Results obtained through LF-NMR are successfully compared to scanning electron microscope and X-ray microcomputed tomography micrographs.
    Lingua originaleEnglish
    pagine (da-a)469-477
    Numero di pagine9
    RivistaInternational Journal of Polymeric Materials and Polymeric Biomaterials
    Volume66
    Stato di pubblicazionePublished - 2017

    All Science Journal Classification (ASJC) codes

    • ???subjectarea.asjc.1600.1602???
    • ???subjectarea.asjc.2500.2507???
    • ???subjectarea.asjc.1500???

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