Characterization of γδ T cells in intestinal mucosa from patients with early onset or long standing inflammatory bowel disease and their correlation with clinical status

Giuseppe Cicero, Elettra Unti, Francesco Dieli, Elena Lo Presti, Serena Meraviglia, Anna Barbara Di Stefano, Filippo Mocciaro, Elettra Unti, Giulia Pecoraro, Elisabetta Conte, Nunzia Scibetta, Roberto Di Mitri, Elisabetta Conte, Filippo Mocciaro, Giulia Maria Pecoraro, Roberto Di Mitri

Risultato della ricerca: Article

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Abstract

Inflammatory bowel disease is a complex chronic inflammatory disease of the human gut with no clear etiology. Traditionally, dysregulated adaptive immune responses play an important role even though accumulating evidence suggest a role also for innate immunity. Because of the well known plasticity of γδ T cells, we investigated their percentage, phenotypical features and effector functions in the intestinal mucosa of early onset and long standing IBD patients, as compared to healthy subjects.
Lingua originaleEnglish
pagine (da-a)1-11
Numero di pagine11
RivistaJournal of Crohn's and Colitis
Stato di pubblicazionePublished - 2019

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All Science Journal Classification (ASJC) codes

  • Gastroenterology

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