Characterization of γδ T cells in intestinal mucosa from patients with early onset or long standing inflammatory bowel disease and their correlation with clinical status

Giuseppe Cicero, Francesco Dieli, Anna Barbara Di Stefano, Elena Lo Presti, Serena Meraviglia, Filippo Mocciaro, Elettra Unti, Giulia Pecoraro, Elisabetta Conte, Nunzia Scibetta, Roberto Di Mitri, Elettra Unti, Elisabetta Conte, Filippo Mocciaro, Giulia Maria Pecoraro, Roberto Di Mitri

Risultato della ricerca: Article

Abstract

Inflammatory bowel disease is a complex chronic inflammatory disease of the human gut with no clear etiology. Traditionally, dysregulated adaptive immune responses play an important role even though accumulating evidence suggest a role also for innate immunity. Because of the well known plasticity of γδ T cells, we investigated their percentage, phenotypical features and effector functions in the intestinal mucosa of early onset and long standing IBD patients, as compared to healthy subjects.
Lingua originaleEnglish
pagine (da-a)1-11
Numero di pagine11
RivistaJournal of Crohn's and Colitis
Stato di pubblicazionePublished - 2019

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Adaptive Immunity
Intestinal Mucosa
Inflammatory Bowel Diseases
Innate Immunity
Healthy Volunteers
Chronic Disease
T-Lymphocytes

All Science Journal Classification (ASJC) codes

  • Gastroenterology

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Characterization of γδ T cells in intestinal mucosa from patients with early onset or long standing inflammatory bowel disease and their correlation with clinical status. / Cicero, Giuseppe; Dieli, Francesco; Di Stefano, Anna Barbara; Lo Presti, Elena; Meraviglia, Serena; Mocciaro, Filippo; Unti, Elettra; Pecoraro, Giulia; Conte, Elisabetta; Scibetta, Nunzia; Di Mitri, Roberto; Unti, Elettra; Conte, Elisabetta; Mocciaro, Filippo; Pecoraro, Giulia Maria; Di Mitri, Roberto.

In: Journal of Crohn's and Colitis, 2019, pag. 1-11.

Risultato della ricerca: Article

Cicero, Giuseppe ; Dieli, Francesco ; Di Stefano, Anna Barbara ; Lo Presti, Elena ; Meraviglia, Serena ; Mocciaro, Filippo ; Unti, Elettra ; Pecoraro, Giulia ; Conte, Elisabetta ; Scibetta, Nunzia ; Di Mitri, Roberto ; Unti, Elettra ; Conte, Elisabetta ; Mocciaro, Filippo ; Pecoraro, Giulia Maria ; Di Mitri, Roberto. / Characterization of γδ T cells in intestinal mucosa from patients with early onset or long standing inflammatory bowel disease and their correlation with clinical status. In: Journal of Crohn's and Colitis. 2019 ; pagg. 1-11.
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AU - Cicero, Giuseppe

AU - Dieli, Francesco

AU - Di Stefano, Anna Barbara

AU - Lo Presti, Elena

AU - Meraviglia, Serena

AU - Mocciaro, Filippo

AU - Unti, Elettra

AU - Pecoraro, Giulia

AU - Conte, Elisabetta

AU - Scibetta, Nunzia

AU - Di Mitri, Roberto

AU - Unti, Elettra

AU - Conte, Elisabetta

AU - Mocciaro, Filippo

AU - Pecoraro, Giulia Maria

AU - Di Mitri, Roberto

PY - 2019

Y1 - 2019

N2 - Inflammatory bowel disease is a complex chronic inflammatory disease of the human gut with no clear etiology. Traditionally, dysregulated adaptive immune responses play an important role even though accumulating evidence suggest a role also for innate immunity. Because of the well known plasticity of γδ T cells, we investigated their percentage, phenotypical features and effector functions in the intestinal mucosa of early onset and long standing IBD patients, as compared to healthy subjects.

AB - Inflammatory bowel disease is a complex chronic inflammatory disease of the human gut with no clear etiology. Traditionally, dysregulated adaptive immune responses play an important role even though accumulating evidence suggest a role also for innate immunity. Because of the well known plasticity of γδ T cells, we investigated their percentage, phenotypical features and effector functions in the intestinal mucosa of early onset and long standing IBD patients, as compared to healthy subjects.

UR - http://hdl.handle.net/10447/356649

M3 - Article

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JO - Journal of Crohn's and Colitis

JF - Journal of Crohn's and Colitis

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