Characteristics of liver cirrhosis in Italy: Evidence for a decreasing role of HCV aetiology

Pier Luigi Almasio, Anna Licata, Mariantonietta Pisaturo, Giovanni Battista Gaeta, Tommaso Stroffolini, Massimo De Luca, Teresa Santantonio, Caterina Furlan, Antonina Smedile, Giuseppina Brancaccio, Caterina Sagnelli, Guido Colloredo, Sergio Babudieri, Filomena Morisco, Maurizio Russello, Nicola Coppola, Bruno Cacopardo, Mario Pirisi, Evangelista Sagnelli, Floriano RosinaAngelo Andriulli, Piero Luigi Almasio, Antonina Smedile

Risultato della ricerca: Articlepeer review

11 Citazioni (Scopus)


Background Previous cross-sectional studies have shown that hepatitis C virus (HCV) infection had been the main agent associated with liver cirrhosis in Italy. Aim To assess epidemiological, laboratory and clinical features of liver cirrhosis in Italy in 2014. Patients Out of the 2557 consecutive subjects evaluated in 16 hospitals located throughout Italy in 2014, 832 (32.6%) had liver cirrhosis and were enrolled in this study. Results The mean age of subjects was 60.3 years, with a male/female ratio of 1.7; 74.9% of cases had Child A cirrhosis and 17.9% superimposed hepatocellular carcinoma. HCV infection, alone or in combination with other aetiologic agents, was responsible of 58.6% of cases, HBV aetiology accounted for the 17.6% and alcohol abuse for the 16.0%. Compared with virus-related cirrhotic patients, those alcohol-related more frequently showed decompensation (p = 0.02). Conclusions Compared to previous surveys performed in 1992 and in 2001, we observe a statistically significant (p 
Lingua originaleEnglish
pagine (da-a)68-72
Numero di pagine5
RivistaEuropean Journal of Internal Medicine
Stato di pubblicazionePublished - 2017

All Science Journal Classification (ASJC) codes

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