Changes in serum Fetuin A and inflammatory markers levels in end stage renal disease (ESRD),effect of a single session haemodialysis

Giulia Bivona, Marcello Ciaccio, Chiara Bellia, Maurizio Li Vecchi, Riccardo Di Sciacca, Giulia Bivona, Marcello Ciaccio, Rossella Iatrino, Chiara Bellia, Epifanio Di Natale, Maurizio Li Vecchi, Riccardo Di Sciacca

Risultato della ricerca: Articlepeer review

24 Citazioni (Scopus)

Abstract

The aim of the present study was to evaluate the effect of a single haemodialysis (HD) session on serum fetuin-A levels, considered a negative acute phase response marker; moreover, we evaluated the behaviour of fibrinogen and high sensitivity C-reactive protein (hsCRP) as acute phase response and chronic/subclinical inflammation markers, respectively, after a single HD session.Serum fetuin-A, albumin, hsCRP and fibrinogen were measured in 72 patients before and after a single HD session.After a single HD session, we observed a significant increase in fibrinogen levels, while fetuin-A levels decreased (p<0.05). Also, hsCRP levels were significantly increased.The significant decrease of fetuin-A levels after a single HD session is consistent with the hypothesis of HD-induced inflammation; activated acute phase response and fetuin-A deficiency might account for increased cardiovascular risk and accelerated atherogenesis in dialysis patients.
Lingua originaleEnglish
pagine (da-a)212-214
RivistaClinical Chemistry and Laboratory Medicine
Volume2008
Stato di pubblicazionePublished - 2008

All Science Journal Classification (ASJC) codes

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  • ???subjectarea.asjc.2700.2704???

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