Cellular localization of mGluR3 and mGluR5 mRNAs in normal and injured rat brain

Giuseppa Mudo', Angela Trovato-Salinaro, Daniele F. Condorelli, Giuseppa Caniglia, Qingzhang Cheng

Risultato della ricerca: Articlepeer review

48 Citazioni (Scopus)

Abstract

In order to understand the role of metabotropic glutamate receptors (mGluRs) in the brain, it is important to know how the mGluRs are differentially expressed among the different cell types. At present, the cellular expression of mGluR3 and mGluR5 has been mostly studied in terms of proteins with observations suggesting the expression of both mGluR3 and mGluR5 in neuronal and in glial cells. In order to verify the brain cell type-expressing mGluR3 and mGluR5 mRNAs, both in normal and injured brain, we performed a double labeling analysis, by in situ hybridization for mGluR3 or mGluR5 mRNA and immunohistochemistry for specific cellular markers.
Lingua originaleEnglish
pagine (da-a)1-13
Numero di pagine13
RivistaBrain Research
Volume1149
Stato di pubblicazionePublished - 2007

All Science Journal Classification (ASJC) codes

  • ???subjectarea.asjc.2800.2800???
  • Molecular Biology
  • Clinical Neurology
  • Developmental Biology

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