Cardiovascular disease in primary sjögren’s syndrome

Francesco Ciccia, Giuliana Guggino, Vasiliki Liakouli, Francesco Carubbi, Paola Di Benedetto, Piero Ruscitti, Onorina Berardicurti, Roberto Giacomelli, Paola Cipriani

Risultato della ricerca: Articlepeer review

2 Citazioni (Scopus)

Abstract

Background: A close relationship between rheumatic diseases and cardiovascular disease (CVD) has been reported, accounting for the higher mortality and morbidity observed in these patients. In the last years, it has been clearly reported that patients affected by primary Sjogren’s syndrome (pSS) experienced an increased risk of CVD. Objective: This review aimed at investigating CVD, traditional cardiovascular (CV) risk factors and possible targeted therapeutic strategies in pSS patients. Method: Available literature concerning CV risk factors in pSS patients has been selected and discussed. Conclusion: Disease-related characteristics and traditional CV risk factors contribute to observed atherosclerotic damage in pSS patients. The pro-inflammatory mediators together with hypertension and type 2 diabetes, which are more prevalent in pSS patients, determine the increased CV burden. Future studies are needed to fully elucidate the role of possible targeted therapies.
Lingua originaleEnglish
pagine (da-a)164-169
Numero di pagine6
RivistaReviews on Recent Clinical Trials
Volume13
Stato di pubblicazionePublished - 2018

All Science Journal Classification (ASJC) codes

  • Pharmacology

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