Cardiac complications in thalassemia: noninvasive detection methods and new directions in the clinical management.

Tommaso Vincenzo Bartolotta, Massimo Midiri, Disma Renda, Tommaso Vincenzo Bartolotta, Luigi Mancuso, Massimo Midiri, Aurelio Maggio, Gaetano Panzarella

Risultato della ricerca: Article

7 Citazioni (Scopus)

Abstract

The natural history of thalassemia has shown substantial change during these years. This applies for each aspect of the pathology (for example, endocrinological, hepatological and psychological) and also for the pathology that has presented and still presents the main cause of death: myocardial dysfunction. In this review, the pathophysiology of cardiac complications, possible role of myocarditis, new knowledge on pathogenesis, and noninvasive detection methods for iron overload in the heart are pointed out. Prophylaxis of cardiomyopathy and new therapy strategies of myocardial dysfunction, including the impact of the new chelation treatment, are discussed.
Lingua originaleEnglish
Numero di pagine0
RivistaExpert Review of Cardiovascular Therapy
Volume2003-09
Stato di pubblicazionePublished - 2003

All Science Journal Classification (ASJC) codes

  • Internal Medicine
  • Cardiology and Cardiovascular Medicine

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