Cardiac arrhythmias in hypertensivesubjects with and without left ventricular hypertrophy compared to the circadian profile of the blood pressure

Mario Barbagallo, Emilio Nardi, Salvatore Corrao, Salvatore Novo, Longo, Novo, Forte, Alaimo, Liquori, Abrignani, Corrao, Barbagallo, Raineri, Emilio Nardi

Risultato della ricerca: Articlepeer review

Abstract

To evaluate possible correlations between cardiac arrhythmias and circadian pattern of blood pressure (BP) and of heart rate (HR), we studied 2 groups of 20 males with stable arterial hypertension of mild to moderate entity, with (Group I) or without (Group II) left ventricular hypertrophy (LVH). In patients with LVH the mean age (56 vs 46 years), the duration of the hypertensive state (48.1 vs 15.7 months), the thickening of interventricular septum (IVS; 13.7 vs 9.6 mm) and of the posterior wall of the left ventricle (13.2 vs 9.2 mm) and the mass of LV (149.8 vs 99.7 g/m2) were significantly greater (p less than 0.01). On the contrary, the 2 groups did not show significant differences concerning casual BP determined in the morning (178.3/108.4 vs 171.5/106.2 mmHg). After a pharmacological washout of 2 weeks, patients underwent a noninvasive, intermittent, monitoring of BP (every 15 min during daytime and every 30 min from 11 pm to 7 am), using a pressure meter II Del Mar Avionics, and a continuous monitoring of ECG for 24 hours, employing an instrument 445/B Del Mar Avionics. Mean 24-hour BP was not different in the 2 groups of patients (161.7/99.0 vs 158.2/98.3 mmHg); however, patients with LVH showed a significantly greater variability of BP in the morning (7 am-3 pm), while mean 24-hour HR was significantly less (71.6 vs 78.2 b/min)
Lingua originaleItalian
pagine (da-a)657-664
Numero di pagine8
RivistaCardiologia
Volume35
Stato di pubblicazionePublished - 1990

All Science Journal Classification (ASJC) codes

  • Cardiology and Cardiovascular Medicine

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