Abstract
| Lingua originale | English |
|---|---|
| pagine (da-a) | 317-330 |
| Numero di pagine | 14 |
| Rivista | Expert Review of Anticancer Therapy |
| Volume | 15 |
| Stato di pubblicazione | Published - 2015 |
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All Science Journal Classification (ASJC) codes
- Oncology
- Pharmacology (medical)
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Cancer and the microbiome: Potential applications as new tumor biomarker. / Castiglia, Marta; Russo, Antonio; Bronte, Giuseppe; Passiglia, Francesco; Gil-Bazo, Ignacio; Peeters, Marc; Castiglia, Marta; Passiglia, Francesco; Shahanavaj, Khan; Carreca, Anna P; Rolfo, Christian; Del Pozo, José Luis; Rolfo, Christian Diego.
In: Expert Review of Anticancer Therapy, Vol. 15, 2015, pag. 317-330.Risultato della ricerca: Article
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TY - JOUR
T1 - Cancer and the microbiome: Potential applications as new tumor biomarker
AU - Castiglia, Marta
AU - Russo, Antonio
AU - Bronte, Giuseppe
AU - Passiglia, Francesco
AU - Gil-Bazo, Ignacio
AU - Peeters, Marc
AU - Castiglia, Marta
AU - Passiglia, Francesco
AU - Shahanavaj, Khan
AU - Carreca, Anna P
AU - Rolfo, Christian
AU - Del Pozo, José Luis
AU - Rolfo, Christian Diego
PY - 2015
Y1 - 2015
N2 - Microbial communities that colonize in humans are collectively described as microbiome. According to conservative estimates, about 15% of all types of neoplasms are related to different infective agents. However, current knowledge is not sufficient to explain how the microbiome contributes to the growth and development of cancers. Large and thorough studies involving colonized, diverse and complex microbiome entities are required to identify microbiome as a potential cancer marker and to understand how the immune system is involved in response to pathogens. This article reviews the existing evidence supporting the enigmatic association of transformed microbiome with the development of cancer through the immunological modification. Ascertaining the connection between microbiome and immunological responses with risk of cancer may direct to explaining significant advances in the etiology of cancer, potentially disclosing a novel paradigm of research for the management and prevention of cancer.
AB - Microbial communities that colonize in humans are collectively described as microbiome. According to conservative estimates, about 15% of all types of neoplasms are related to different infective agents. However, current knowledge is not sufficient to explain how the microbiome contributes to the growth and development of cancers. Large and thorough studies involving colonized, diverse and complex microbiome entities are required to identify microbiome as a potential cancer marker and to understand how the immune system is involved in response to pathogens. This article reviews the existing evidence supporting the enigmatic association of transformed microbiome with the development of cancer through the immunological modification. Ascertaining the connection between microbiome and immunological responses with risk of cancer may direct to explaining significant advances in the etiology of cancer, potentially disclosing a novel paradigm of research for the management and prevention of cancer.
UR - http://hdl.handle.net/10447/249741
UR - http://www.future-drugs.com/loi/era
M3 - Article
VL - 15
SP - 317
EP - 330
JO - Expert Review of Anticancer Therapy
JF - Expert Review of Anticancer Therapy
SN - 1473-7140
ER -