Brain mapping as helpful tool in brain glioma surgical treatment—Toward the “perfect surgery”?

Giuseppe Roberto Giammalva, Domenico Iacopino, Fabio Barone, Rosario Maugeri, Francesca Graziano, Corrado D’Arrigo, Salvatore Cicero, Giuseppe Roberto Giammalva, Walter Tagnese, Domenico Gerardo Iacopino, Nicola Alberio, Caterina D'Arrigo

Risultato della ricerca: Articlepeer review

16 Citazioni (Scopus)


Gliomas are the most common primary malignant brain tumours in adults, representing nearly 80%, with poor prognosis in their high-grade forms. Several variables positively affect the prognosis of patients with high-grade glioma: young age, tumour location, radiological features, recurrence, and the opportunity to perform post-operative adjuvant therapy. Low-grade gliomas are slow-growing brain neoplasms of adolescence and young-adulthood, preferentially involving functional areas, particularly the eloquent ones. It has been demonstrated that early surgery and higher extent rate ensure overall longer survival time regardless of tumour grading, but nowadays, functional preservation that is as complete as possible is imperative. To achieve the best surgical results, along with the best functional results, intraoperative mapping and monitoring of brain functions, as well as different anaesthesiology protocols for awake surgery are nowadays being widely adopted. We report on our experience at our institution with 28 patients affected by malignant brain tumours who underwent brain mapping-aided surgical resection of neoplasm: 20 patients underwent awake surgical resection and 8 patients underwent asleep surgical resection. An analysis of the results and a review of the literature has been performed.
Lingua originaleEnglish
pagine (da-a)192-203
Numero di pagine12
RivistaBrain Sciences
Stato di pubblicazionePublished - 2018

All Science Journal Classification (ASJC) codes

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