Biotechnology of Rhodococcus for the production of valuable compounds

Elena Piacenza, Alessandro Presentato, Martina Cappelletti, Raymond J. Turner, Elena Piacenza, Andrea Firrincieli, Davide Zannoni

Risultato della ricerca: Articlepeer review

7 Citazioni (Scopus)


Bacteria belonging to Rhodococcus genus represent ideal candidates for microbial biotechnology applications because of theirmetabolic versatility, ability to degrade a wide range of organic compounds, and resistance to various stress conditions, such asmetal toxicity, desiccation, and high concentration of organic solvents. Rhodococcus spp. strains have also peculiar biosyntheticactivities that contribute to their strong persistence in harsh and contaminated environments and provide them a competitiveadvantage over other microorganisms. This review is focused on the metabolic features of Rhodococcus genus and their potentialuse in biotechnology strategies for the production of compounds with environmental, industrial, and medical relevance such asbiosurfactants, bioflocculants, carotenoids, triacylglycerols, polyhydroxyalkanoate, siderophores, antimicrobials, and metalbasednanostructures. These biosynthetic capacities can also be exploited to obtain high value-added products from low-costsubstrates (industrial wastes and contaminants), offering the possibility to efficiently recover valuable resources and providingpossible waste disposal solutions. Rhodococcus spp. strains have also recently been pointed out as a source of novel bioactivemolecules highlighting the need to extend the knowledge on biosynthetic capacities of members of this genus and their potentialutilization in the framework of bioeconomy.
Lingua originaleEnglish
pagine (da-a)8567-8594
Numero di pagine28
RivistaApplied Microbiology and Biotechnology
Stato di pubblicazionePublished - 2020

All Science Journal Classification (ASJC) codes

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