Biochemical and chemical characterization of Cynara cardunculus L. extract and its potential use as co-adjuvant therapy of chronic myeloid leukemia

Medicine & Life Sciences

• Cynara 100%
• Leukemia, Myelogenous, Chronic, BCR-ABL Positive 52%
• Imatinib Mesylate 40%
• cynaropicrin 29%
• Phosphotransferases 16%
• Cynara scolymus 12%
• Chromosomes, Human, Pair 22 9%
• Chromosomes, Human, Pair 9 9%
• Mediterranean Diet 9%
• Flowers 9%
• Cell Line 8%
• Therapeutics 8%
• Gene Fusion 8%
• Methanol 7%
• Chromatography 7%
• Drug Resistance 6%
• High Pressure Liquid Chromatography 5%
• Leukocytes 5%
• Cell Survival 5%
• Proteins 5%
• Down-Regulation 4%
• Western Blotting 4%
• Cell Proliferation 4%
• Neoplasms 4%
• Polymerase Chain Reaction 4%
• Drug Therapy 4%
• Mutation 3%
• Growth 3%
• In Vitro Techniques 3%

Chemical Compounds

• Imatinib 74%
• Cynaropicrin 38%
• Chemical Substance Type 13%
• Phosphotransferase Inhibitor 12%
• Resistance 12%
• Antiproliferative 9%
• Cell Viability 9%
• Chemical Method 9%
• Mutation 8%
• Protein 8%
• Chromatography 7%
• Gas Chromatography Mass Spectrometry (GCMS) 7%
• Methanol 6%
• Molecule 3%