Abstract

In order to understand the mechanism underlying the physiological adaptation of purely aerobic workout, we investigated the effect of 2 months of training on nine males (17-22 year-old) middle distance running agonistic athletes. Blood sample was collected in the morning to analyze: hematological parameters, lipid profile, liver function enzymes [glutamate oxaloacetate transaminase, glutamate pyruvate transaminase, gamma-glutamyl transferase (γ-GT)] and skeletal and myocardial markers of muscle damage [creatin kinase (CK) and creatin kinase MB (CK-MB)]. Endurance training, as it implies high oxygen consumption, should increase reactive oxygen species, but it has been shown that exercise leads to increased activation of antioxidant defenses. In fact, serum levels of γ-GT enzyme and total CK were not increased. On the other hand, a statistical significant reduction of CKMB has been observed. There were not variations in hematological parameters. As far as the anthropometric value is concerned, after two months of training there was a change in weight (P<0.0001). Finally, any oxidative and biological stress was highlighted in the middle distance runners but, since this is a preliminary study, it would be of interest to replicate the study on a larger sample.
Lingua originaleEnglish
pagine (da-a)70-73
Numero di pagine4
RivistaJOURNAL OF BIOLOGICAL RESEARCH
Volume87
Stato di pubblicazionePublished - 2014

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phosphotransferases (kinases)
Blood
Phosphotransferases
Transaminases
Glutamic Acid
blood
Physiological Adaptation
Oxaloacetic Acid
Physiological Stress
gamma-glutamyltransferase
athletes
liver function
Enzymes
Transferases
enzymes
blood serum
Pyruvic Acid
alanine transaminase
Oxygen Consumption
aspartate transaminase

All Science Journal Classification (ASJC) codes

  • Biochemistry, Genetics and Molecular Biology(all)
  • Plant Science
  • Biochemistry, medical

Cita questo

@article{c2251619c99041ea8d9e71011595c731,
title = "Biochemical adaptations in middle-distance runners: an assessment of blood and anthropometric parameters",
abstract = "In order to understand the mechanism underlying the physiological adaptation of purely aerobic workout, we investigated the effect of 2 months of training on nine males (17-22 year-old) middle distance running agonistic athletes. Blood sample was collected in the morning to analyze: hematological parameters, lipid profile, liver function enzymes [glutamate oxaloacetate transaminase, glutamate pyruvate transaminase, gamma-glutamyl transferase (γ-GT)] and skeletal and myocardial markers of muscle damage [creatin kinase (CK) and creatin kinase MB (CK-MB)]. Endurance training, as it implies high oxygen consumption, should increase reactive oxygen species, but it has been shown that exercise leads to increased activation of antioxidant defenses. In fact, serum levels of γ-GT enzyme and total CK were not increased. On the other hand, a statistical significant reduction of CKMB has been observed. There were not variations in hematological parameters. As far as the anthropometric value is concerned, after two months of training there was a change in weight (P<0.0001). Finally, any oxidative and biological stress was highlighted in the middle distance runners but, since this is a preliminary study, it would be of interest to replicate the study on a larger sample.",
author = "Patrizia Proia and Antonio Palma and {Di Majo}, Danila and Marco Giammanco and Marcello Traina and Gabriella Schiera",
year = "2014",
language = "English",
volume = "87",
pages = "70--73",
journal = "JOURNAL OF BIOLOGICAL RESEARCH",
issn = "2284-0230",

}

TY - JOUR

T1 - Biochemical adaptations in middle-distance runners: an assessment of blood and anthropometric parameters

AU - Proia, Patrizia

AU - Palma, Antonio

AU - Di Majo, Danila

AU - Giammanco, Marco

AU - Traina, Marcello

AU - Schiera, Gabriella

PY - 2014

Y1 - 2014

N2 - In order to understand the mechanism underlying the physiological adaptation of purely aerobic workout, we investigated the effect of 2 months of training on nine males (17-22 year-old) middle distance running agonistic athletes. Blood sample was collected in the morning to analyze: hematological parameters, lipid profile, liver function enzymes [glutamate oxaloacetate transaminase, glutamate pyruvate transaminase, gamma-glutamyl transferase (γ-GT)] and skeletal and myocardial markers of muscle damage [creatin kinase (CK) and creatin kinase MB (CK-MB)]. Endurance training, as it implies high oxygen consumption, should increase reactive oxygen species, but it has been shown that exercise leads to increased activation of antioxidant defenses. In fact, serum levels of γ-GT enzyme and total CK were not increased. On the other hand, a statistical significant reduction of CKMB has been observed. There were not variations in hematological parameters. As far as the anthropometric value is concerned, after two months of training there was a change in weight (P<0.0001). Finally, any oxidative and biological stress was highlighted in the middle distance runners but, since this is a preliminary study, it would be of interest to replicate the study on a larger sample.

AB - In order to understand the mechanism underlying the physiological adaptation of purely aerobic workout, we investigated the effect of 2 months of training on nine males (17-22 year-old) middle distance running agonistic athletes. Blood sample was collected in the morning to analyze: hematological parameters, lipid profile, liver function enzymes [glutamate oxaloacetate transaminase, glutamate pyruvate transaminase, gamma-glutamyl transferase (γ-GT)] and skeletal and myocardial markers of muscle damage [creatin kinase (CK) and creatin kinase MB (CK-MB)]. Endurance training, as it implies high oxygen consumption, should increase reactive oxygen species, but it has been shown that exercise leads to increased activation of antioxidant defenses. In fact, serum levels of γ-GT enzyme and total CK were not increased. On the other hand, a statistical significant reduction of CKMB has been observed. There were not variations in hematological parameters. As far as the anthropometric value is concerned, after two months of training there was a change in weight (P<0.0001). Finally, any oxidative and biological stress was highlighted in the middle distance runners but, since this is a preliminary study, it would be of interest to replicate the study on a larger sample.

UR - http://hdl.handle.net/10447/127067

M3 - Article

VL - 87

SP - 70

EP - 73

JO - JOURNAL OF BIOLOGICAL RESEARCH

JF - JOURNAL OF BIOLOGICAL RESEARCH

SN - 2284-0230

ER -