Binding properties of mono-(6-deoxy-6-amino)-beta-cyclodextrins towards p-nitroaniline derivatives: a polarimetric study

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Abstract

Polarimetry was used in order to investigate the formation of supramolecular complexes between mono-6-amino-β-cyclodextrin and various p-nitroaniline derivatives at two different pH values. Comparison with the behaviour of native β-cyclodextrin gave us the opportunity to consider the effect exerted by the presence of charged groups, having different solvation requirements, on the binding equilibrium. Data offer some support to the hypothesis of 'dynamic co-inclusion' of solvent molecules within the host-guest complex.
Lingua originaleEnglish
pagine (da-a)10413-10417
Numero di pagine5
RivistaTetrahedron
Volume65
Stato di pubblicazionePublished - 2009

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Cyclodextrins
Derivatives
Polarimeters
Solvation
Molecules
4-nitroaniline
6-amino-6-deoxy-beta-cyclodextrin

All Science Journal Classification (ASJC) codes

  • Biochemistry
  • Drug Discovery
  • Organic Chemistry

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title = "Binding properties of mono-(6-deoxy-6-amino)-beta-cyclodextrins towards p-nitroaniline derivatives: a polarimetric study",
abstract = "Polarimetry was used in order to investigate the formation of supramolecular complexes between mono-6-amino-β-cyclodextrin and various p-nitroaniline derivatives at two different pH values. Comparison with the behaviour of native β-cyclodextrin gave us the opportunity to consider the effect exerted by the presence of charged groups, having different solvation requirements, on the binding equilibrium. Data offer some support to the hypothesis of 'dynamic co-inclusion' of solvent molecules within the host-guest complex.",
author = "{Lo Meo}, {Paolo Maria Giuseppe} and Michelangelo Gruttadauria and Renato Noto and Francesca D'Anna and Serena Riela",
year = "2009",
language = "English",
volume = "65",
pages = "10413--10417",
journal = "Tetrahedron",
issn = "0040-4020",
publisher = "Elsevier Limited",

}

TY - JOUR

T1 - Binding properties of mono-(6-deoxy-6-amino)-beta-cyclodextrins towards p-nitroaniline derivatives: a polarimetric study

AU - Lo Meo, Paolo Maria Giuseppe

AU - Gruttadauria, Michelangelo

AU - Noto, Renato

AU - D'Anna, Francesca

AU - Riela, Serena

PY - 2009

Y1 - 2009

N2 - Polarimetry was used in order to investigate the formation of supramolecular complexes between mono-6-amino-β-cyclodextrin and various p-nitroaniline derivatives at two different pH values. Comparison with the behaviour of native β-cyclodextrin gave us the opportunity to consider the effect exerted by the presence of charged groups, having different solvation requirements, on the binding equilibrium. Data offer some support to the hypothesis of 'dynamic co-inclusion' of solvent molecules within the host-guest complex.

AB - Polarimetry was used in order to investigate the formation of supramolecular complexes between mono-6-amino-β-cyclodextrin and various p-nitroaniline derivatives at two different pH values. Comparison with the behaviour of native β-cyclodextrin gave us the opportunity to consider the effect exerted by the presence of charged groups, having different solvation requirements, on the binding equilibrium. Data offer some support to the hypothesis of 'dynamic co-inclusion' of solvent molecules within the host-guest complex.

UR - http://hdl.handle.net/10447/40311

M3 - Article

VL - 65

SP - 10413

EP - 10417

JO - Tetrahedron

JF - Tetrahedron

SN - 0040-4020

ER -